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Table 5 Multivariate Cox proportional hazard analysis for OS in ADC

From: Role of Synaptophysin, Chromogranin and CD56 in adenocarcinoma and squamous cell carcinoma of the lung lacking morphological features of neuroendocrine differentiation: a retrospective large-scale study on 1170 tissue samples

Variable HR (CI95) p value
Stage II 2.76 (1.576–3.581) < 0.001a
Stage III 4.649 (3.276–6.597) < 0.001a
Stage IV 6.729 (3.726–12.155) < 0.001a
Age (> 59 versus < 59 years) 1.036 (0.776–1.384) 0.809
Gender (female versus male) 0.564 (0.420–0.757) < 0.001
Neuroendocrine marker (positivity versus negativity) 0.876 (0.616–1.247) 0.463
  1. n = 617
  2. aas compared to Stage I
  3. OS overall survival