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Table 2 Performance of PIVKA-II for the diagnosis of AFP-negative HCC patients

From: PIVKA-II serves as a potential biomarker that complements AFP for the diagnosis of hepatocellular carcinoma

 

AUC(95%CI)

Cutoff value

Sensitivity(%)(95%CI)

Specificity(%)(95%CI)

HCC vs Healthy controls

0.88 (0.82–0.94)

38.75mAU/ml

78.33 (66.38–86.88)

91.3 (85.42–94.96)

HCC vs Benign liver diseases

0.76 (0.67–0.85)

42.07 ng/ml

74.19 (62.12–83.45)

82.68 (75.16–88.27)