OPLS-DA model diagnostics | |||||
---|---|---|---|---|---|
Predictive component | R2X | R2Y | Q2 | ||
0.0995 | 0.477 | 0.28 | |||
Orthogonal components | R2X(o) | ||||
0.548 | |||||
0.107 | |||||
cv-ANOVA p value | 0.0001 | ||||
Misclassification table | |||||
Members | Correct | ||||
preCHT | 1 | 100% | |||
postCHT | 23 | 100% | |||
List of the important metabolites from the OPLS-DA model | |||||
Name | ppm | p(corr) | p value | Median ratio [%] | |
Metabolites increased after induction chemotherapy | |||||
1 | Lipids | 0.9 | 0.76 | < 0.000 | 12.73 |
1.3 | 0.57 | < 0.000 | 18.58 | ||
5.3 | 0.69 | < 0.000 | 17.38 | ||
Metabolites decreased after induction chemotherapy | |||||
2 | Alanine | 1.48 | 0.33 | 0.0008 | 14.21 |
3 | NAG | 2.07 | 0.12 | 0.0002 | 9.03 |
4 | Glucose | 3.24 | 0.31 | 0.04 | 9.4 |
3.42 | 0.43 | 0.042 | 8.11 | ||
3.44 | 0.48 | 0.038 | 8.46 | ||
3.51 | 0.43 | 0.036 | 9.54 | ||
3.56 | 0.46 | 0.04 | 9.33 | ||
3.72 | 0.55 | 0.039 | 9.59 | ||
3.76 | 0.43 | 0.031 | 8.3 | ||
3.83 | 0.39 | 0.019 | 8.57 | ||
3.9 | 0.48 | 0.028 | 9.34 | ||
5.2 | 0.32 | 0.025 | 9.57 |