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Fig. 1 | BMC Cancer

Fig. 1

From: Analytical validation of the Percepta genomic sequencing classifier; an RNA next generation sequencing assay for the assessment of Lung Cancer risk of suspicious pulmonary nodules

Fig. 1

Workflow of Percepta GSC. Total RNA is extracted, quantified, and used as input in a library prep procedure which enriches for the coding transcriptome. After the sample is sequenced, a Percepta GSC score is calculated from an ensemble of machine learning algorithms utilizing clinical and genomic features. The Percepta GSC score is used to refine a patient’s pre-test risk stratification and a patient report is produced with the post-test risk. Assay performance was analyzed through reproducibility experiments and other studies demonstrating analytical sensitivity and analytical specificity

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