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Table 3 Multivariable Cox analysis of academic vs. non-academic (reference) stratified by treatment combinations

From: The impact of treatment facility type on the survival of brain metastases patients regardless of the primary cancer type

Combinations

N (%)

Multivariable Cox analysis HR ((95% CI)

 

Only brain RT

17,879 (19.7)

0.84 (0.82–0.87)

0.001

Only other RT

5790 (6.4)

0.88 (0.83–0.93)

0.001

Only chemotherapy

7033 (7.8)

0.83 (0.78–0.88)

0.001

Only surgery

335 (0.4)

…

 

Chemotherapy plus brain RT

31,341 (34.5)

0.85 (0.83–0.87)

0.001

Chemotherapy plus other RT

9663 (10.7)

0.86 (0.82–0.90)

0.001

Surgery plus brain RT

660 (0.7)

0.78 (0.64–0.94)

0.009

Surgery plus other RT

78 (0.1)

…

 

Surgery plus chemotherapy

280 (0.3)

0.74 (0.55–0.99)

0.046

Surgery plus chemotherapy plus brain RT

1063 (1.2)

0.75 (0.64–0.88)

0.003

Surgery plus chemotherapy plus other RT

210 (0.2)

…

 

No surgery no chemotherapy no RT

16,398 (18.0)

0.91 (0.88–0.95)

0.001

  1. RT radiation therapy; The results of only surgery, surgery plus other RT, and surgery plus chemotherapy plus other RT were not significant