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Table 1 Multivariable logistic analysis with the probability of being treated in academic hospital in BMs patients

From: The impact of treatment facility type on the survival of brain metastases patients regardless of the primary cancer type

Variable

Academic

31,579 (34.1%)

Non-academic

61,054 (65.9%)

Total

92,633

OR (95% CI)

P

Age at diagnosis, Median (range)

64.00 (40–90)

66.00 (40–90)

65.00 (40–90)

0.99 (0.99–0.99)

0.001

Sex

Male

15,998 (50.7)

31,130 (51.0)

47,128 (50.9)

Reference

 

Female

15,581 (49.3)

29,924 (49.0)

45,505 (49.1)

1.02 (0.99–1.05)

0.23

Race

White

24,790 (79.4)

53,343 (87.9)

78,133 (85.0)

Reference

 

Black

5005 (16.0)

5596 (9.2)

10,601 (11.5)

1.94 (1.86–2.03)

0.001

Other

1429 (4.6)

1785 (2.9)

3214 (3.5)

1.58 (1.47–1.70)

0.001

Unknown

355

330

685

  

Education

> = 13% NHD

15,228 (48.3)

28,622 (47.0)

43,850 (47.4)

1.07 (1.04–1.11)

0.001

< 13% NHD

16,276 (51.7)

32,304 (53.0)

48,580 (52.6)

Reference

 

Unknown

75

128

203

  

Income

> = $35,000

17,473 (55.5)

32,571 (53.5)

50,044 (54.2)

Reference

 

< 35,000

14,005 (44.5)

28,319 (46.5)

42,324 (45.8)

0.84 (0.81–0.87)

0.001

Unknown

101

164

265

  

Place of Living

Urban

30,510 (98.2)

57,724 (97.3)

88,234 (97.6)

Reference

 

Rural

547 (1.8)

1597 (2.7)

2144 (2.4)

0.73 (0.66–0.80)

0.001

Unknown

522

1733

2255

  

Insurance Status

Yes

29,057 (96.5)

56,998 (97.3)

86,055 (94.4)

Reference

 

No

1934 (3.5)

3195 (2.7)

5129 (5.6)

1.04 (0.98–1.11)

0.17

Unknown

588

861

1449

  

Charlson/Deyo Score

0

21,032 (66.6)

36,986 (60.6)

58,018 (62.6)

Reference

 

1

7132 (22.6)

16,130 (26.4)

23,262 (25.1)

0.82 (0.79–0.84)

0.001

> = 2

3415 (10.8)

7938 (13.0)

11,353 (12.3)

0.81 (0.77–0.85)

0.001

Primary site surgery

Yes

1061 (3.4)

1604 (2.6)

2665 (2.9)

Ref

 

No

30,518 (95.6)

59,450 (97.4)

89,968 (97.1)

0.90 (0.83–0.98)

0.02

Chemotherapy

Yes

17,687 (56.0)

32,419 (53.1)

50,106 (54.1)

Reference

 

No

13,892 (44.0)

28,635 (46.9)

42,527 (45.9)

0.96 (0.93–0.99)

0.007

Radiation Therapy

Yes

23,373 (74.0)

43,737 (71.6)

67,110 (72.5)

Reference

 

No

8206 (26.0)

17,317 (28.4)

25,523 (27.5)

0.96 (0.93–0.99)

0.02

Immunotherapy

Yes

1217 (3.9)

1811 (3.0)

3028 (3.3)

Ref

 

No

30,362 (96.1)

59,243 (93.0)

89,605 (96.7)

0.90 (0.83–0.97)

0.009

Year of Diagnosis

2010–2013

20,224 (64.0)

40,100 (65.7)

60,324 (65.1)

0.93 (0.90–0.96)

0.001

2014–2015

11,355 (36.0)

20,954 (34.3)

32,309 (34.9)

Reference

 

Primary Cancer Type

Breast

14,141 (4.5)

2522 (4.1)

3936 (4.3)

0.69 (0.62–0.77)

0.001

NSCLC

21,250 (67.3)

39,575 (64.8)

60,825 (65.7)

0.76 (0.70–0.83)

0.001

SCLC

4406 (14.0)

10,378 (17.0)

14,784 (15.9)

0.64 (0.59–0.70)

0.001

Other lung

1779 (5.6)

4450 (8.0)

6229 (6.7)

0.65 (0.59–0.72)

0.001

Melanoma

1224 (3.9)

1825 (2.3)

3049 (3.3)

1.02 (0.92–1.15)

0.67

Colorectal

393 (1.2)

726 (1.2)

1119 (1.2)

0.74 (0.64–0.86)

0.001

Renal cell

1113 (3.5)

1578 (2.6)

2691 (2.9)

Ref

 
  1. NHD no high school degree