Subject characteristics | Univariable | Multivariable | ||
---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Age in years | ||||
 18–40 | Ref | 1.00 | Ref | 1.00 |
 41–64 | 1.311 (0.945–1.817) | 0.105 | 1.189 (0.845–1.673) | 0.321 |
  ≥ 65 | 1.373 (0.959–1.966) | 0.083 | 1.128 (0.780–1.633) | 0.522 |
Surgery primary site | ||||
 No | Ref | 1.00 | Ref | 1.00 |
 yes | 0.687 (0.474–0.994) | 0.046 | 0.821 (0.557–1.210) | 0.319 |
Lung Met | ||||
 No | Ref | 1.00 | Ref | 1.00 |
 Yes | 1.416 (1.136–1.765) | 0.002 | 1.471 (1.171–1.847) | 0.001 |
Bone Met | ||||
 No | Ref | 1.00 | Ref | 1.00 |
 Yes | 1.240 (0.982–1.564) | 0.070 | 1.114 (0.880–1.410) | 0.370 |
Chemotherapy | ||||
 Yes | Ref | 1.00 | Ref | 1.00 |
 No/Unknown | 3.117 (2.475–3.924) | < 0.001 | 3.229 (2.551–4.086) | < 0.001 |