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Table 3 Univariable and multivariable Cox regression analysis of overall survival in cervical cancer patients with hepatic metastasis in SEER database (2010–2015)

From: Incidence, clinical risk and prognostic factors for liver metastasis in patients with cervical cancer: a population-based retrospective study

Subject characteristics Univariable Multivariable
HR (95% CI) P-value HR (95% CI) P-value
Age in years
 18–40 Ref 1.00 Ref 1.00
 41–64 1.244 (0.910–1.699) 0.171 1.207 (0.872–1.672) 0.257
  ≥ 65 1.402 (1.002–1.961) 0.048 1.253 (0.886–1.771) 0.202
Surgery primary site
 No Ref 1.00 Ref 1.00
 yes 0.668 (0.481–0.927) 0.016 0.716 (0.506–1.012) 0.058
Lung Met
 No Ref 1.00 Ref 1.00
 Yes 1.384 (1.128–1.698) 0.002 1.451 (1.175–1.793) 0.001
Bone Met
 No Ref 1.00 Ref 1.00
 Yes 1.244 (1.000–1.549) 0.050 1.160 (0.929–1.448) 0.190
Radiotherapy
 Yes Ref 1.00 Ref 1.00
 No/ Unknown 1.583 (1.297–1.933) < 0.001 1.555 (1.262–1.915) < 0.001
Chemotherapy
 Yes Ref 1.00 Ref 1.00
 No/Unknown 3.390 (2.738–4.198) < 0.001 3.312 (2.654–4.134) < 0.001
  1. Notes: Met, Metastasis