Table 4 Comparison of characteristics, efficacy and safety in patients undergoing ultrasound-guided lung biopsy between 16-gauge and 18-gauge core biopsy needle when number of pleural surfaces crossed was more than 2
Variable | Overall cohort | Propensity-score matched cohort | ||||
|---|---|---|---|---|---|---|
16-gauge (n = 65) | 18-gauge (n = 217) | P value | 16-gauge (n = 63) | 18-gauge (n = 63) | P value | |
Age (years) | 57.1 ± 15.9 | 57.8 ± 13.7 | 0.719 | 57.4 ± 16.0 | 59.1 ± 12.7 | 0.514 |
Gender | ||||||
Male/female | 37/28 | 142/75 | 0.211 | 37/26 | 35/28 | 0.719 |
Patient position | ||||||
Supine/prone/lateral | 25/30/10 | 70/107/40 | 0.626 | 23/10/30 | 20/10/33 | 0.839 |
Emphysema on CT | 3 (4.6%) | 17 (7.8%) | 0.541 | 3 (4.8%) | 4 (6.3%) | 1.000 |
Location of pulmonary lesion (%) | ||||||
Left upper lobe | 5 (7.7%) | 49 (22.6%) | 0.071 | 5 (7.9%) | 11 (17.5%) | 0.251 |
Left lower lobe | 20 (30.8%) | 53 (24.4%) | 20 (31.8%) | 13 (20.6%) | ||
Right upper lobe | 23 (35.3%) | 57 (26.3%) | 23 (36.5%) | 18 (28.6%) | ||
Right middle lobe | 7 (10.8%) | 18 (8.3%) | 6 (9.5%) | 9 (14.3%) | ||
Right lower lobe | 10 (15.4%) | 40 (18.4%) | 9 (14.3%) | 12 (19.0%) | ||
Diameter of lesion (cm) | 5.0 ± 2.3 | 5.2 ± 2.6 | 0.475 | 5.0 ± 2.3 | 5.0 ± 2.7 | 0.968 |
< 5/≥5 | 28/37 | 100/117 | 0.669 | 27/36 | 31/32 | 0.475 |
Proportion of necrosis in the lesion | ||||||
< 50%/≥50% | 57/8 | 187/30 | 0.753 | 55/8 | 57/6 | 0.571 |
Success rate (%) | 63 (96.9%) | 202 (93.1%) | 0.254 | 61 (96.8%) | 59 (93.7%) | 0.676 |
Malignant | 36 (55.4%) | 122 (56.2%) | 0.469 | 35 (55.6%) | 32 (50.8%) | 0.664 |
Benign | 27 (41.5%) | 80 (36.9%) | 26 (41.2%) | 27 (42.9%) | ||
Non-diagnostic | 2 (3.1%) | 15 (6.9%) | 2 (3.2%) | 4 (6.3%) | ||
Complication rate (%) | 11 (16.9%) | 22 (10.1%) | 0.135 | 11 (17.5%) | 5 (7.9%) | 0.108 |
Pneumothorax | 1 (1.5%) | 8 (3.7%) | 0.690 | 1 (1.6%) | 2 (3.2%) | 1.000 |
Major | 1 (1.5%) | 2 (0.9%) | 0.546 | 1 (1.6%) | 1 (1.6%) | 1.000 |
Minor | 0 (0%) | 6 (3.8%) | 0.387 | 0 (0%) | 1 (1.6%) | 1.000 |
Hemorrhage | 6 (9.2%) | 13 (6.0%) | 0.398 | 6 (9.5%) | 3 (4.8%) | 1.000 |
Major | 0 (0%) | 0 (0%) | – | 0 (0%) | 0 (0%) | – |
Minor | 6 (9.2%) | 13 (6.0%) | 0.398 | 6 (9.5%) | 3 (4.8%) | 0.489 |
Vasovagal reaction | 4 (6.2%) | 1 (0.4%) | 0.012 | 4 (6.3%) | 0 (0%) | 0.127 |