Fig. 5
From: PTEN loss correlates with T cell exclusion across human cancers
The Correlation of PI3K-AKT-mTOR pathway activation with PTEN expression and the T cells infiltration. The Correlation of PI3K-AKT-mTOR pathway activation (represented by p-AKT [phosphorylated at Thr308 or Ser473], p-mTOR [phosphorylated at Ser2448], and ssGSEA score of PI3K pathway) with PTEN expression and the T cells infiltration was evaluated by Pearson Correlation analysis. Node color is determined by correlation, and node size indicates the significance of correlation. Only nodes with Correlation significance (P value) < 0.05 were shown. Abbreviations: Tem, effector memory T cells; Tcm, central memory T cells; full terms of cancer abbreviation were shown in Fig. 2