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Fig. 2 | BMC Cancer

Fig. 2

From: PTEN loss correlates with T cell exclusion across human cancers

Fig. 2

Positive correlation between expression of PTEN and T-cell-inflamed genes. Dot plots of PTEN mRNA expression (log transferred) on x-axis and T-cell-inflamed genes (CD4, CD8A) mRNA expression (log transferred) on y-axis per tumor types. Correlation coefficients (R value) and P value of Pearson Correlation were shown for each tumor type. mRNA expression of PTEN was positively correlated with expression level of CD4 and CD8 in multiple tumor types. Abbreviations: BLCA, Bladder Urothelial Carcinoma; BRCA, Breast invasive carcinoma; COAD, Colon adenocarcinoma; GBM, Glioblastoma multiforme; HNSC, Head and Neck squamous cell carcinoma; KICH, Kidney Chromophobe; KIRC, Kidney renal clear cell carcinoma; KIRP, Kidney renal papillary cell carcinoma; LGG, Brain Lower Grade Glioma; LIHC, Liver hepatocellular carcinoma; LUAD, Lung adenocarcinoma; LUSC, Lung squamous cell carcinoma; OV, Ovarian serous cystadenocarcinoma; PAAD, Pancreatic adenocarcinoma; PRAD, Prostate adenocarcinoma; READ, Rectum adenocarcinoma; SARC, Sarcoma; SKCM, Skin Cutaneous Melanoma; STAD, Stomach adenocarcinoma; THCA, Thyroid carcinoma; UCEC, Uterine Corpus Endometrial Carcinoma

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