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Fig. 1 | BMC Cancer

Fig. 1

From: Downregulated ZNF132 predicts unfavorable outcomes in breast Cancer via Hypermethylation modification

Fig. 1

Expression analysis of ZNF132 in BC. a ZNF132 was downregulated in 1104 BC tissues and 114 matched pairs of BC tissues compared with adjacent normal tissues based on the TCGA database. b Data from the Oncomine 4.5 database also revealed that mRNA expression of ZNF132 was significantly reduced in BC tissues. c ZNF132 expression was reduced in different BC molecular subgroups, including luminal A, luminal B, HER2-positive, Triple negative BC. Data were presented as mean ± SD. ***, P < 0.001 for comparison with the control. d qRT-PCR assay was performed to assess the mRNA expression of ZNF132 in 19 cases of BC tissues. e Immunohistochemistry analysis of ZNF132 in BC and adjacent normal tissues (× 20). f ZNF132 expression was determined using Western blot analysis in six BC cell lines and normal breast epithelial cells. GAPDH was used as internal control

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