Table 2 Genotypic model analysis of the relationship between SNPs and risk of astrocytoma
Gene | SNP ID | Model | Genotype | Controls | Cases | Crude | Adjusted by gender and age | ||
|---|---|---|---|---|---|---|---|---|---|
OR (95% CI) | p | OR (95% CI) | p | ||||||
ST6GAL1 | rs2239611 | Codominant | G/G | 225 (59.4%) | 244 (66.8%) | 1.00 | 0.034 | 1.00 | 0.044 |
A/G | 138 (36.4%) | 107 (29.4%) | 0.81 (0.39–1.69) | 0.87 (0.41–1.83) | |||||
A/A | 16 (4.2%) | 14 (3.8%) | 0.71 (0.52–0.98) | 0.72 (0.53–0.99) | |||||
Dominant | G/G | 225 (59.4%) | 244 (66.8) | 1.00 | 0.035 | 1.00 | 0.049 | ||
A/G-A/A | 154 (40.6) | 121 (33.2%) | 0.72 (0.54–0.98) | 0.74 (0.55–1.00) | |||||
Recessive | G/G-A/G | 363 (95.8%) | 351 (96.2%) | 1.00 | 0.789 | 1.00 | 0.932 | ||
A/A | 16 (4.2%) | 14 (3.8%) | 0.90 (0.44–1.88) | 0.97 (0.46–2.02) | |||||
Additive | – | – | – | 0.78 (0.61–1.01) | 0.059 | 0.80 (0.62–1.04) | 0.089 | ||