Fig. 8From: Multi gene mutation signatures in colorectal cancer patients: predict for the diagnosis, pathological classification, staging and prognosisThe relationship between tumor microenvironment (TME) and gene mutation status in the mutated gene signatures. Patients with mutant TP53, APC, KRAS, PIK3CA had lower stromal score, immune score, ESTIMATE core and higher tumor purity compared with non-mutated patients, and the TME in patients with BRAF, ATM, LRP1B, FAT4, FMN2, TRRAP, and ROS1 mutations showed the opposite trend. a Comparison of stromal score between mutated and non-mutated patients. b Comparison of immune score between mutated and non-mutated patients. c Comparison of ESTIMATE score between mutated and non-mutated patients. d Comparison of tumor purity between mutated and non-mutated patientsBack to article page