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Fig. 2 | BMC Cancer

Fig. 2

From: Multi gene mutation signatures in colorectal cancer patients: predict for the diagnosis, pathological classification, staging and prognosis

Fig. 2

The mutated gene signature for the diagnosis of colorectal cancer. Mutations of TP53, APC, KRAS, BRAF and ATM covering 97.55% of TCGA population and 84.9% validation patients, and they can be used to distinguish between cancer and paracancer. a The mutation distribution of TP53, APC, KRAS, BRAF and ATM inTCGA and validation patients. Different colors represented different mutation types, and red represented frame-shift mutation, yellow in-frame mutation, green missense mutation, blue nonsense mutation and black splice site mutation; b The Venn diagram of mutations of TP53, APC, KRAS, BRAF and ATM in TCGA population; c The Venn diagram of mutations of TP53, APC, KRAS, BRAF and ATM in validation population

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