Table 1 Clinicopathological Characteristics of the study cohort
Characteristics | Training cohort(n = 201) | Validation cohort(n = 68) | P Value |
|---|---|---|---|
Gender | Â | Â | 0.639 |
 Female | 50 (24.9) | 15 (22.1) |  |
 Male | 151 (75.1) | 53 (77.9) |  |
Age | 62.7 ± 11.6 | 62.8 ± 11.9 | 0.956 |
KFI | Â | Â | 0.257 |
  < 2 | 125 (62.19) | 37 (54.41) |  |
  ≥ 2 | 76 (37.81) | 31 (45.59) |  |
Smoking | Â | Â | 0.679 |
 No | 121 (60.2) | 39 (57.35) |  |
 Yes | 80 (39.8) | 29 (42.65) |  |
pT | Â | Â | 0.359 |
 T1 | 41 (20.4) | 12 (17.65) |  |
 T2 | 63 (31.34) | 21 (30.88) |  |
 T3 | 54 (26.87) | 15 (22.06) |  |
 T4 | 43 (21.39) | 20 (29.41) |  |
pN | Â | Â | 0.259 |
 N0 | 31 (15.42) | 9 (13.24) |  |
 N1 | 53 (26.37) | 14 (20.59) |  |
 N2 | 110 (54.73) | 40 (58.82) |  |
 N3 | 7 (3.48) | 5 (7.35) |  |
AJCC Stage | Â | Â | 0.544 |
 III | 61 (30.3) | 18 (26.5) |  |
 IV | 140 (69.7) | 50 (73.5) |  |
Perineural invasion | Â | Â | 0.931 |
 No | 120 (59.7) | 41 (60.3) |  |
 Yes | 81 (40.3) | 27 (39.7) |  |
Tumor differentiation | Â | Â | 0.640 |
 Well differentiated | 87 (43.3) | 25 (36.8) |  |
 Moderately differentiated | 51 (25.4) | 19 (27.9) |  |
 Poorly differentiated | 63 (31.3) | 24 (35.3) |  |
Depth of tumor invasion | Â | Â | 0.268 |
  < 20 mm | 127 (63.2) | 48 (70.6) |  |
  ≥ 20 mm | 74 (36.8) | 20 (29.4) |  |
Number of Positive Nodes | Â | Â | 0.648 |
 0 | 84 (41.79) | 31 (45.6) |  |
 1–2 | 58 (28.86) | 21 (30.9) |  |
 3–4 | 34 (16.92) | 9 (13.2) |  |
  ≥ 5 | 25 (12.44) | 7 (10.3) |  |
Lymphovascular invasion (%) | Â | Â | 0.189 |
 No | 41 (20.4) | 9 (13.24) |  |
 Yes | 160 (79.6) | 59 (86.76) |  |
Primary Tumor Site | Â | Â | 0.570 |
 Tongue | 69 (34.33) | 21 (30.88) |  |
 Floor of mouth | 60 (29.85) | 25 (36.76) |  |
 Other | 72 (35.82) | 22 (32.35) |  |
Extracapsular extension | Â | Â | 0.537 |
 No | 158 (78.61) | 51 (75) |  |
 Yes | 43 (21.39) | 17 (25) |  |
Bone invasion | Â | Â | 0.366 |
 No | 119 (59.2) | 36 (52.94) |  |
 Yes | 82 (40.8) | 32 (47.06) |  |
Safety Margins | Â | Â | 0.408 |
  < 5 mm | 45 (22.39) | 12 (17.65) |  |
  ≥ 5 mm | 156 (77.61) | 56 (82.35) |  |
SII | Â | Â | 0.580 |
  < 535.5 | 120 (59.7) | 38 (55.88) |  |
  ≥ 535.5 | 81 (40.3) | 30 (44.12) |  |
NLR | Â | Â | 0.480 |
  < 2.8 | 125 (62.19) | 39 (57.35) |  |
  ≥ 2.8 | 76 (37.81) | 29 (42.65) |  |
PLR | Â | Â | 0.761 |
  < 162.5 | 114 (56.72) | 40 (58.82) |  |
  ≥ 162.5 | 87 (43.28) | 28 (41.18) |  |