| the HNM group | the BM group | ||||
---|---|---|---|---|---|---|
Training cohort (%) | Validation cohort (%) | P value | Training cohort (%) | Validation cohort (%) | P value | |
Total | 10,551 (70.0) | 4520 (30.0) | Â | 38,876 (70.0) | 16,658 (30.0) | Â |
Age | Â | Â | 0.21 | Â | Â | 0.748 |
  ≤ 58 | 3349 (31.7) | 1467 (32.5) |  | 20,275 (52.2) | 8666 (52.0) |  |
 59–78 | 4885 (46.3) | 2023 (44.8) |  | 14,790 (38.0) | 6324 (38.0) |  |
  ≥ 79 | 2317 (22.0) | 1030 (22.8) |  | 3811 (9.8) | 1668 (10.0) |  |
Sex | Â | Â | 0.62 | Â | Â | 0.836 |
 Male | 7653 (72.5) | 3260 (72.1) |  | 20,359 (52.4) | 8707 (52.3) |  |
 Female | 2898 (27.5) | 1260 (27.9) |  | 18,517 (47.6) | 7951 (47.7) |  |
Race | Â | Â | 0.911 | Â | Â | 0.31 |
 White | 10,452 (99.1) | 4476 (99.0) |  | 38,267 (98.4) | 16,417 (98.6) |  |
 aOthers | 99 (0.9) | 44 (1.0) |  | 609 (1.6) | 241 (1.4) |  |
Histology | Â | Â | 0.31 | Â | Â | 0.067 |
 NM | 1680 (15.9) | 672 (14.9) |  | 5448 (14.0) | 2457 (14.7) |  |
 LMM | 3328 (31.5) | 1470 (32.5) |  | 2589 (6.7) | 1049 (6.3) |  |
 SMM | 4306 (40.8) | 1862 (41.2) |  | 27,177 (69.9) | 11,571 (69.5) |  |
 bOther Melanoma | 1237 (11.7) | 516 (11.4) |  | 3662 (9.4) | 1581 (9.5) |  |
Thickness | Â | Â | 0.096 | Â | Â | 0.012 |
  < 0.6 mm | 4691 (44.5) | 2026 (44.8) |  | 17,866 (46.0) | 7435 (44.6) |  |
 0.6–0.79 mm | 987 (9.4) | 466 (10.3) |  | 4711 (12.1) | 2061 (12.4) |  |
 0.8–1.0 mm | 827 (7.8) | 321 (7.1) |  | 3699 (9.5) | 1527 (9.2) |  |
 1.01–2.0 mm | 1666 (15.8) | 728 (16.1) |  | 6073 (15.6) | 2673 (16.0) |  |
 2.01–4.0 mm | 1268 (12.0) | 491 (10.9) |  | 3666 (9.4) | 1671 (10.0) |  |
  > 4.0 mm | 1112 (10.5) | 488 (10.8) |  | 2861 (7.4) | 1291 (7.8) |  |
Ulceration | Â | Â | 0.459 | Â | Â | 0.43 |
 No | 8841 (83.8) | 3810 (84.3) |  | 33,040 (85.0) | 14,113 (84.7) |  |
 Yes | 1710 (16.2) | 710 (15.7) |  | 5836 (15.0) | 2545 (15.3) |  |
Stage | Â | Â | 0.795 | Â | Â | 0.159 |
 Localized | 9051 (85.8) | 3893 (86.1) |  | 34,591 (89.0) | 14,729 (88.4) |  |
 Regional | 1320 (12.5) | 548 (12.1) |  | 3731 (9.6) | 1677 (10.1) |  |
 Distant | 180 (1.7) | 79 (1.7) |  | 554 (1.4) | 252 (1.5) |  |
Metastases | Â | Â | 0.937 | Â | Â | 0.251 |
 No | 10,405 (98.6) | 4456 (98.6) |  | 38,501 (99.0) | 16,479 (98.9) |  |
 Yes | 146 (1.4) | 64 (1.4) |  | 375 (1.0) | 179 (1.1) |  |
Surgery | Â | Â | 0.545 | Â | Â | 0.591 |
 No | 245 (2.3) | 97 (2.1) |  | 773 (2.0) | 319 (1.9) |  |
 Yes | 10,306 (97.7) | 4423 (97.9) |  | 38,103 (98.0) | 16,339 (98.1) |  |