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Table 1 Comparison of head and neck melanoma (HNM) with body melanoma (BM)

From: Comparing the characteristics and predicting the survival of patients with head and neck melanoma versus body melanoma: a population-based study

 

HNM

BM

P value

Total

15,071 (21)c

55,534 (79)d

 

Age, mean (y)

64.6

57.2

 

Age, median (y)

67

58

 

Age (n %)

  

< 0.001

  ≤ 58

4816 (32.0)

28,941 (52.1)

 

 59–78

6908 (45.8)

21,114 (38.0)

 

  ≥ 79

3347 (22.2)

5479 (9.9)

 

Sex (n %)

  

< 0.001

 Male

10,913 (72.4)

29,066 (52.3)

 

 Female

4158 (27.6)

26,468 (47.7)

 

Race (n %)

  

< 0.001

 White

14,928 (99.1)

54,684 (98.5)

 

 aOthers

143 (0.9)

850 (1.5)

 

Histology (n %)

  

< 0.001

 NM

2352 (15.6)

7905 (14.2)

 

 LMM

4798 (31.8)

3638 (6.6)

 

 SMM

6168 (40.9)

38,748 (69.8)

 

 bOther Melanoma

1753 (11.6)

5243 (9.4)

 

Thickness (n %)

  

< 0.001

  < 0.6 mm

6717 (44.6)

25,301 (45.6)

 

 0.6–0.79 mm

1453 (9.6)

6772 (12.2)

 

 0.8–1.0 mm

1148 (7.6)

5226 (9.4)

 

 1.01–2.0 mm

2394 (15.9)

8746 (15.7)

 

 2.01–4.0 mm

1759 (11.7)

5337 (9.6)

 

  > 4.0 mm

1600 (10.6)

4152 (7.5)

 

Ulceration (n %)

  

0.004

 No

12,651 (83.9)

47,153 (84.9)

 

 Yes

2420 (16.1)

8381 (15.1)

 

Stage (n %)

  

< 0.001

 Localized

12,944 (85.9)

49,320 (88.8)

 

 Regional

1868 (12.4)

5408 (9.7)

 

 Distant

259 (1.7)

806 (1.5)

 

Metastases (n %)

  

< 0.001

 No

14,861 (98.6)

54,980 (99.0)

 

 Yes

210 (1.4)

554 (1.0)

 

Surgery (n %)

  

0.021

 No

342 (2.3)

1092 (2.0)

 

 Yes

14,729 (97.7)

54,442 (98.0)

 

Radiation (n %)

  

< 0.001

 No/Unknown

14,519 (96.3)

55,055 (99.1)

 

 Yes

552 (3.7)

479 (0.9)

 

Chemotherapy (n %)

  

0.474

 No/Unknown

14,869 (98.7)

54,833 (98.7)

 

 Yes

202 (1.3)

701 (1.3)

 

Survival months, mean

60.59

67.76

< 0.001

OS (n %)

  

< 0.001

 Alive

10,942 (72.6)

46,547 (83.8)

 

 Dead

4129 (27.4)

8987 (16.2)

 

CSS (n %)

  

< 0.001

 Alive

13,431 (89.1)

51,448 (92.6)

 

 Dead

1640 (10.9)

4086 (7.4)

 

5-year OS rate

(%, mean ± SD)

74.4 ± 0.4

85.8 ± 0.2

< 0.001

5-year CSS rate

(%, mean ± SD)

88.1 ± 0.3

92.5 ± 0.1

< 0.001

  1. NM nodular melanoma, LMM Lentigo maligna melanoma, SSM superficial spreading melanoma, CSS cancer-specific survival, OS overall survival, SD standard deviation
  2. P values were obtained using the Pearson χ2 test or Fisher exact test. Bold values indicate statistical significance less than 0.05
  3. a Others = black, Asian or pacific islander, American indian/Alaska native
  4. b Other melanoma: International Classification of Diseases for Oncology-O-3, codes 8722–8723, 8730, 8740–8741, 8744–8746, 8761, 8770–8774, 8780
  5. cHNM constitute 21% of all cutaneous melanomas
  6. dBM constitute 79% of all cutaneous melanomas
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BMC Cancer

ISSN: 1471-2407

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