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Table 4 Odds ratios [95% confidence intervals] for cancer risk behaviours at age 24 years (imputed sample)

From: Young adult cancer risk behaviours originate in adolescence: a longitudinal analysis using ALSPAC, a UK birth cohort study

Harmful drinking

Unadjusted analysis

p-value

Partially adjusted analysisa

p-value

Fully adjusted analysisb

p-value

Odds ratios [95% CIs]

Odds ratios [95% CIs]

Odds ratios [95% CIs]

Q1 (referent category)

1

p ≤ 0.001

1

p ≤ 0.001

1

p ≤ 0.001

Q2

1.20 [0.92,1.55]

1.27 [0.98,1.65]

1.29 [0.99,1.68]

Q3

1.54 [1.21,1.96]

1.69 [1.32,2.17]

1.71 [1.33,2.19]

Q4

1.71 [1.33,2.18]

2.03 [1.57,2.62]

2.04 [1.57,2.65]

Linear association

1.04 [1.03,1.06]

p ≤ 0.001

1.06 [1.04,1.08]

p ≤ 0.001

1.06 [1.04,1.08]

p ≤ 0.001

Daily smoking

 Q1 (referent category)

1

p ≤ 0.001

1

p ≤ 0.001

1

p ≤ 0.001

 Q2

1.69 [1.14,2.51]

1.61 [1.08,2.40]

1.57 [1.05,2.3]

 Q3

2.73 [1.86,3.99]

2.57 [1.75,3.79]

2.50[1.69,3.70]

 Q4

5.89 [4.04,8.58]

5.71 [3.90,8.38]

5.37[3.64,7.93]

Linear association

1.18 [1.15,1.22]

p ≤ 0.001

1.18 [1.15,1.22]

p ≤ 0.001

1.18[1.15,1.21]

p ≤ 0.001

Nicotine dependence

 Q1 (referent category)

1

p ≤ 0.001

1

p ≤ 0.001

1

p ≤ 0.001

 Q2

1.50 [0.87,2.58]

1.42 [0.82,2.46]

1.37 [0.79,2.38]

 Q3

2.54 [1.57,4.12]

2.36 [1.46,3.84]

2.26 [1.39,3.69]

 Q4

5.93 [3.75,9.36]

5.61 [3.53,8.93]

5.10 [3.19,8.17]

Linear association

1.19 [1.15, 1.23]

p ≤ 0.001

1.18 1.14, 1.23]

p ≤ 0.001

1.18 [1.13, 1.22]

p ≤ 0.001

Obesityc

 Q1 (referent category)

1

p ≤ 0.001

1

p ≤ 0.001

1

p ≤ 0.001

 Q2

1.54 [1.05,2.28]

1.48 [1.00,2.19]

1.52 [0.98,2.34]

 Q3

2.70 [1.89,3.84]

2.53 1.77,3.61]

2.41 [1.62,3.58]

 Q4

5.74 [4.12,8.00]

5.26 [3.76,7.37]

4.84 [3.33,7.03]

Linear association

1.18 [1.15, 1.21]

p ≤ 0.001

1.17 [1.14, 1.20]

p ≤ 0.001

1.16 [1.13, 1.19]

p ≤ 0.001

Waist circumferencec

 Q1 (referent category)

1

p ≤ 0.001

1

p ≤ 0.001

1

p ≤ 0.001

 Q2

1.34 [1.08,1.68]

1.25 1.00,1.57]

1.24 [0.97,1.59]

 Q3

1.77 [1.43,2.19]

1.59 [1.28,1.98]

1.53 [1.21,1.94]

 Q4

3.17 [2.55,3.93]

2.66 [2.13,3.32]

2.48 [1.94,3.16]

Linear association

1.12 [1.10,1.14]

p ≤ 0.001

1.10 [1.08, 1.12]

p ≤ 0.001

1.09 [1.07, 1.12]

p ≤ 0.001

Waist-to-hip ratioc

 Q1 (referent category)

1

p ≤ 0.001

1

p ≤ 0.001

1

p ≤ 0.001

 Q2

1.47 1.04,2.10]

1.27 [0.88,1.83]

1.29 [0.87,1.91]

 Q3

1.72 [1.23,2.40]

1.37 [0.97,1.95]

1.32 [0.90,1.94]

 Q4

2.87 [2.09,3.93]

1.98 [1.42,2.78]

1.88 [1.30,2.71]

Linear association

1.10 [1.07, 1.13]

p ≤ 0.001

1.07 [1.04, 1.09]

p ≤ 0.001

1.06 [1.03, 1.09]

p ≤ 0.001

  1. a Adjusted for sex, IQ, parental socio-economic status (maternal education, parental social class, household equivalised income and housing tenure) and adverse childhood experiences (ACEs)
  2. b Additionally adjusted for maternal cannabis use, maternal harmful alcohol use and maternal smoking and child depressive symptoms (SMFQ), child antisocial behaviour and child total difficulties score (SDQ)
  3. c These analyses were additionally, adjusted for birthweight and gestational age in the partially adjusted analysis and maternal obesity, maternal physical inactivity and maternal unhealthy diet in the fully adjusted analysis
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BMC Cancer

ISSN: 1471-2407

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