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Table 4 Odds ratios [95% confidence intervals] for cancer risk behaviours at age 24 years (imputed sample)

From: Young adult cancer risk behaviours originate in adolescence: a longitudinal analysis using ALSPAC, a UK birth cohort study

Harmful drinking Unadjusted analysis p-value Partially adjusted analysisa p-value Fully adjusted analysisb p-value
Odds ratios [95% CIs] Odds ratios [95% CIs] Odds ratios [95% CIs]
Q1 (referent category) 1 p ≤ 0.001 1 p ≤ 0.001 1 p ≤ 0.001
Q2 1.20 [0.92,1.55] 1.27 [0.98,1.65] 1.29 [0.99,1.68]
Q3 1.54 [1.21,1.96] 1.69 [1.32,2.17] 1.71 [1.33,2.19]
Q4 1.71 [1.33,2.18] 2.03 [1.57,2.62] 2.04 [1.57,2.65]
Linear association 1.04 [1.03,1.06] p ≤ 0.001 1.06 [1.04,1.08] p ≤ 0.001 1.06 [1.04,1.08] p ≤ 0.001
Daily smoking
 Q1 (referent category) 1 p ≤ 0.001 1 p ≤ 0.001 1 p ≤ 0.001
 Q2 1.69 [1.14,2.51] 1.61 [1.08,2.40] 1.57 [1.05,2.3]
 Q3 2.73 [1.86,3.99] 2.57 [1.75,3.79] 2.50[1.69,3.70]
 Q4 5.89 [4.04,8.58] 5.71 [3.90,8.38] 5.37[3.64,7.93]
Linear association 1.18 [1.15,1.22] p ≤ 0.001 1.18 [1.15,1.22] p ≤ 0.001 1.18[1.15,1.21] p ≤ 0.001
Nicotine dependence
 Q1 (referent category) 1 p ≤ 0.001 1 p ≤ 0.001 1 p ≤ 0.001
 Q2 1.50 [0.87,2.58] 1.42 [0.82,2.46] 1.37 [0.79,2.38]
 Q3 2.54 [1.57,4.12] 2.36 [1.46,3.84] 2.26 [1.39,3.69]
 Q4 5.93 [3.75,9.36] 5.61 [3.53,8.93] 5.10 [3.19,8.17]
Linear association 1.19 [1.15, 1.23] p ≤ 0.001 1.18 1.14, 1.23] p ≤ 0.001 1.18 [1.13, 1.22] p ≤ 0.001
Obesityc
 Q1 (referent category) 1 p ≤ 0.001 1 p ≤ 0.001 1 p ≤ 0.001
 Q2 1.54 [1.05,2.28] 1.48 [1.00,2.19] 1.52 [0.98,2.34]
 Q3 2.70 [1.89,3.84] 2.53 1.77,3.61] 2.41 [1.62,3.58]
 Q4 5.74 [4.12,8.00] 5.26 [3.76,7.37] 4.84 [3.33,7.03]
Linear association 1.18 [1.15, 1.21] p ≤ 0.001 1.17 [1.14, 1.20] p ≤ 0.001 1.16 [1.13, 1.19] p ≤ 0.001
Waist circumferencec
 Q1 (referent category) 1 p ≤ 0.001 1 p ≤ 0.001 1 p ≤ 0.001
 Q2 1.34 [1.08,1.68] 1.25 1.00,1.57] 1.24 [0.97,1.59]
 Q3 1.77 [1.43,2.19] 1.59 [1.28,1.98] 1.53 [1.21,1.94]
 Q4 3.17 [2.55,3.93] 2.66 [2.13,3.32] 2.48 [1.94,3.16]
Linear association 1.12 [1.10,1.14] p ≤ 0.001 1.10 [1.08, 1.12] p ≤ 0.001 1.09 [1.07, 1.12] p ≤ 0.001
Waist-to-hip ratioc
 Q1 (referent category) 1 p ≤ 0.001 1 p ≤ 0.001 1 p ≤ 0.001
 Q2 1.47 1.04,2.10] 1.27 [0.88,1.83] 1.29 [0.87,1.91]
 Q3 1.72 [1.23,2.40] 1.37 [0.97,1.95] 1.32 [0.90,1.94]
 Q4 2.87 [2.09,3.93] 1.98 [1.42,2.78] 1.88 [1.30,2.71]
Linear association 1.10 [1.07, 1.13] p ≤ 0.001 1.07 [1.04, 1.09] p ≤ 0.001 1.06 [1.03, 1.09] p ≤ 0.001
  1. a Adjusted for sex, IQ, parental socio-economic status (maternal education, parental social class, household equivalised income and housing tenure) and adverse childhood experiences (ACEs)
  2. b Additionally adjusted for maternal cannabis use, maternal harmful alcohol use and maternal smoking and child depressive symptoms (SMFQ), child antisocial behaviour and child total difficulties score (SDQ)
  3. c These analyses were additionally, adjusted for birthweight and gestational age in the partially adjusted analysis and maternal obesity, maternal physical inactivity and maternal unhealthy diet in the fully adjusted analysis