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Table 2 Potential prognostic factors for overall survival in patients aged ≥65 years with pancreatic cancer

From: The prognostic significance of combined geriatric nutritional risk index and psoas muscle volume in older patients with pancreatic cancer

  Univariate analysis Multivariate analysis
Variables HR 95% CI P HR 95% CI P
Sex (male vs. female) 1.771 1.043–3.006 0.034 1.463 0.814–2.629 0.204
Age (≥ 75 years vs. <  75 years) 1.111 0.675–1.830 0.678    
Body mass index (<  20.5 mm vs. ≥ 20.5 mm) 2.946 1.781–4.873 <  0.001 2.048 1.105–3.796 0.023
Tumor size (≥ 20.0 mm vs. <  20.0 mm) 2.383 1.170–4.855 0.017 2.829 1.297–6.174 0.009
Tumor location (head vs. body and tail) 1.135 0.688–1.874 0.620    
Histological grading for primary tumor (G1 vs. other) 0.667 0.372–1.194 0.173    
Lymph node metastasis (present vs. absent) 2.736 1.604–4.666 <  0.001 2.552 1.466–4.443 0.001
ASA-PS (3 vs. 1 or 2) 1.500 0.837–2.687 0.173    
Preoperative CA19–9 (≥ 152.8 U/mL vs. <  152.8 U/mL) 1.987 1.185–3.330 0.009 1.272 0.749–2.161 0.373
Combination of the GNRI and PMV
(Group C vs. Group A and Group B
3.852 2.321–6.393 < 0.001 2.866 1.490–5.513 0.002
  1. Abbreviations: HR Hazard ratio; CI Confidence interval; G1 Well-differentiated; ASA-PS American Society of Anesthesiologists physical status; CA19–9 Carbohydrate antigen 19–9; GNRI Geriatric nutritional risk index; PMV Total psoas muscle volume; Group A, both high GNRI and high PMV; Group B, high GNRI or high PMV (but not both); Group C, both low GNRI and low PMV
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