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Table 1 Numbers and percentages by deprivation and co-variable status: (A) women diagnosed 1988–2010 and (B) 2005–2010

From: Are socio-economic inequalities in breast cancer survival explained by peri-diagnostic factors?

  Total 1 - Least deprived 2 3 4 5 - Most deprived p-value2 p-value non-miss.3
N % N % N % N % N % N %
A All cases1 21,802 100.0 4,898 22.5 5,335 24.5 4,979 22.8 4,048 18.6 2,542 11.7   
Vital status
Alive 13,594 62.4 3,252 66.4 3,481 65.2 3,121 62.7 2,336 57.7 1,404 55.2 <0.001  
Dead 8,208 37.6 1,646 33.6 1,854 34.8 1,858 37.3 1,712 42.3 1,138 44.8
Age at diagnosis
Mean (sd) 63.2 (14.6) 61.8 (13.9) 63.3 (14.5) 63.4 (14.7) 64.4 (15.0) 63.3 (15.2) <0.001  
15-49 4,367 20.0 1,056 21.6 1,020 19.1 970 19.5 756 18.7 565 22.2 <0.001
50-59 5,072 23.3 1,228 25.1 1,283 24.0 1,155 23.2 893 22.1 513 20.2
60-69 5,198 23.8 1,212 24.7 1,309 24.5 1,195 24.0 913 22.6 569 22.4
70-79 3,885 17.8 833 17.0 905 17.0 891 17.9 766 18.9 490 19.3
80+ 3,280 15.0 569 11.6 818 15.3 768 15.4 720 17.8 405 15.9
Period of diagnosis
1989-1992 447 2.1 93 1.9 112 2.1 115 2.3 80 2.0 47 1.8 <0.001  
1993-1995 1,070 4.9 284 5.8 230 4.3 248 5.0 201 5.0 107 4.2
1996-1998 1,595 7.3 370 7.6 393 7.4 339 6.8 287 7.1 206 8.1
1999-2001 2,585 11.9 639 13.0 616 11.5 569 11.4 475 11.7 286 11.3
2002-2004 3,605 16.5 904 18.5 798 15.0 792 15.9 688 17.0 423 16.6
2005-2007 5,870 26.9 1,371 28.0 1,259 23.6 1,439 28.9 1,097 27.1 704 27.7
2008-2010 6,630 30.4 1,237 25.3 1,927 36.1 1,477 29.7 1,220 30.1 769 30.3
Stage at diagnosis
Stage I 4,912 22.5 1,116 22.8 1,286 24.1 1,137 22.8 878 21.7 495 19.5 <0.001 <0.01
Stage II 6,525 29.9 1,460 29.8 1,577 29.6 1,545 31.0 1,175 29.0 768 30.2
Stage III 1,046 4.8 203 4.1 264 4.9 245 4.9 212 5.2 122 4.8
Stage IV 516 2.4 99 2.0 127 2.4 120 2.4 98 2.4 72 2.8
Missing 8,803 40.4 2,020 41.2 2,081 39.0 1,932 38.8 1,685 41.6 1,085 42.7
Smoking status
Non-smoker 9,464 43.4 2,362 48.2 2,442 45.8 2,165 43.5 1,625 40.1 870 34.2 0.077 <0.001
Current smoker 4,491 20.6 875 17.9 950 17.8 999 20.1 942 23.3 725 28.5
Ex-smoker 6,705 30.8 1,449 29.6 1,711 32.1 1,539 30.9 1,227 30.3 779 30.6
Current or Ex-smoker 384 1.8 52 1.1 64 1.2 92 1.8 101 2.5 75 3.0
Missing 758 3.5 160 3.3 168 3.1 184 3.7 153 3.8 93 3.7
Alcohol drinking status
Non-drinker 3,178 14.6 555 11.3 649 12.2 721 14.5 693 17.1 560 22.0 <0.001 <0.001
Current drinker 12,294 56.4 2,841 58.0 3,184 59.7 2,803 56.3 2,195 54.2 1,271 50.0
Ex-drinker 1,420 6.5 234 4.8 302 5.7 304 6.1 332 8.2 248 9.8
Missing 4,910 22.5 1,268 25.9 1,200 22.5 1,151 23.1 828 20.5 463 18.2   
A All cases1 21,802 100.0 4,898 22.5 5,335 24.5 4,979 22.8 4,048 18.6 2,542 11.7   
Body mass index (kg/m2)
<20 1,188 5.4 275 5.6 301 5.6 249 5.0 214 5.3 149 5.9 0.290 <0.001
20-24 7,195 33.0 1,903 38.9 1,828 34.3 1,565 31.4 1,210 29.9 689 27.1
25-29 6,455 29.6 1,390 28.4 1,611 30.2 1,528 30.7 1,171 28.9 755 29.7
30+ 4,542 20.8 812 16.6 978 18.3 1,081 21.7 986 24.4 685 26.9
Missing 2,422 11.1 518 10.6 617 11.6 556 11.2 467 11.5 264 10.4
Charlson Comorbidity Score (CPRD data only)
None recorded 16,662 76.4 4,024 82.2 4,133 77.5 3,758 75.5 2,949 72.9 1,798 70.7 <0.001  
1 3,597 16.5 640 13.1 842 15.8 869 17.5 741 18.3 505 19.9
2 1,033 4.7 162 3.3 251 4.7 227 4.6 229 5.7 164 6.5
3+ 510 2.3 72 1.5 109 2.0 125 2.5 129 3.2 75 3.0
Consultations prior to diagnosis
None recorded 1,070 4.9 199 4.1 247 4.6 262 5.3 231 5.7 131 5.2 <0.001  
1 to 5 8,076 37.0 1,939 39.6 2,007 37.6 1,862 37.4 1,428 35.3 840 33.0
6 to 10 6,131 28.1 1,377 28.1 1,518 28.5 1,402 28.2 1,117 27.6 717 28.2
11+ 6,525 29.9 1,383 28.2 1,563 29.3 1,453 29.2 1,272 31.4 854 33.6
Mean (sd) 8.8 (8.3) 8.5 (7.8) 8.6 (8.0) 8.6 (8.1) 9.2 (8.8) 9.6 (9.1)
Breast-related consultations prior to diagnosis
None recorded 11,214 51.4 2,383 48.7 2,721 51.0 2,628 52.8 2,186 54.0 1,296 51.0 <0.001  
1 8,939 41.0 2,100 42.9 2,186 41.0 2,008 40.3 1,577 39.0 1,068 42.0
2+ 1,649 7.6 415 8.5 428 8.0 343 6.9 285 7.0 178 7.0
Mean (sd) 0.58 (0.72) 0.62 (0.71) 0.60 (0.76) 0.56 (0.69) 0.55 (0.72) 0.58 (0.68)
Number of breast symptoms reported prior to diagnosis
None recorded 10,406 47.7 2,298 46.9 2,542 47.6 2,428 48.8 1,967 48.6 1,171 46.1 <0.01  
1 9,664 44.3 2,182 44.5 2,356 44.2 2,218 44.5 1,759 43.5 1,149 45.2
2 1,343 6.2 328 6.7 332 6.2 273 5.5 244 6.0 166 6.5
3+ 389 1.8 90 1.8 105 2.0 60 1.2 78 1.9 56 2.2
Number of days since last symptom report to diagnosis4
Mean (range) 32.2 (1-547) 32.7 (1-541) 32.7 (1-547) 32.4 (1-545) 30.7 (1-541) 32.2 (1-541) <0.05  
Referrals prior to diagnosis               
None recorded 14,257 65.4 3,073 62.7 3,539 66.3 3,282 65.9 2,703 66.8 1,660 65.3 <0.001  
1 7,044 32.3 1,691 34.5 1,667 31.2 1,590 31.9 1,261 31.2 835 32.8
2+ 501 2.3 134 2.7 129 2.4 107 2.1 84 2.1 47 1.8   
B Cases diagnosed 2005-20101 12,500 100.0 2,608 20.9 3,186 25.5 2,916 23.3 2,317 18.5 1,473 11.8   
Charlson comorbidity score (HES data only)
None recorded 11,774 94.2 2,512 96.3 3,032 95.2 2,742 94.0 2,137 92.2 1,351 91.7 <0.001  
1 451 3.6 64 2.5 101 3.2 107 3.7 110 4.7 69 4.7
2 174 1.4 18 0.7 31 1.0 50 1.7 41 1.8 34 2.3
3+ 101 0.8 14 0.5 22 0.7 17 0.6 29 1.3 19 1.3
Charlson comorbidity score (CPRD or HES data)
None recorded 8,931 71.4 2,059 78.9 2,332 73.2 2,042 70.0 1,548 66.8 950 64.5 <0.001  
1 2,185 17.5 353 13.5 534 16.8 541 18.6 455 19.6 302 20.5
2 865 6.9 124 4.8 206 6.5 211 7.2 183 7.9 141 9.6
3+ 519 4.2 72 2.8 114 3.6 122 4.2 131 5.7 80 5.4
Time from diagnosis to first major surgery
On or before diagnosis 919 7.4 176 6.7 202 6.3 206 7.1 169 7.3 166 11.3 0.064 0.106
<=1 month 4,583 36.7 936 35.9 1,139 35.8 1,079 37.0 888 38.3 541 36.7
<=2 months 2,733 21.9 574 22.0 727 22.8 645 22.1 504 21.8 283 19.2
>2 months 588 4.7 114 4.4 153 4.8 141 4.8 115 5.0 65 4.4
None recorded 3,677 29.4 808 31.0 965 30.3 845 29.0 641 27.7 418 28.4
Number of days from diagnosis to first major surgery5
Mean (sd) 34.3 (28.4) 34.1 (27.8) 35.0 (28.9) 34.7 (29.8) 33.7 (27.4) 33.6 (27.3) 0.051  
  1. 1Row percentages
  2. 2P-value for association between index variable and deprivation (multinomial regression for categorical variables and non-parametric tests for trend for continuous variables, see text)
  3. 3P-value for association between index variable and deprivation, excluding missing category (multinomial regression for categorical variables and non-parametric tests for trend for continuous variables, see text)
  4. 4Amongst the 6,302 patients who reported a breast symptom prior to diagnosis
  5. 5Amongst the 7,904 patients who had surgery after diagnosis