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Table 1 Numbers and percentages by deprivation and co-variable status: (A) women diagnosed 1988–2010 and (B) 2005–2010

From: Are socio-economic inequalities in breast cancer survival explained by peri-diagnostic factors?

 

Total

1 - Least deprived

2

3

4

5 - Most deprived

p-value2

p-value non-miss.3

N

%

N

%

N

%

N

%

N

%

N

%

A All cases1

21,802

100.0

4,898

22.5

5,335

24.5

4,979

22.8

4,048

18.6

2,542

11.7

  

Vital status

 Alive

13,594

62.4

3,252

66.4

3,481

65.2

3,121

62.7

2,336

57.7

1,404

55.2

<0.001

 

 Dead

8,208

37.6

1,646

33.6

1,854

34.8

1,858

37.3

1,712

42.3

1,138

44.8

Age at diagnosis

 Mean (sd)

63.2

(14.6)

61.8

(13.9)

63.3

(14.5)

63.4

(14.7)

64.4

(15.0)

63.3

(15.2)

<0.001

 

 15-49

4,367

20.0

1,056

21.6

1,020

19.1

970

19.5

756

18.7

565

22.2

<0.001

 50-59

5,072

23.3

1,228

25.1

1,283

24.0

1,155

23.2

893

22.1

513

20.2

 60-69

5,198

23.8

1,212

24.7

1,309

24.5

1,195

24.0

913

22.6

569

22.4

 70-79

3,885

17.8

833

17.0

905

17.0

891

17.9

766

18.9

490

19.3

 80+

3,280

15.0

569

11.6

818

15.3

768

15.4

720

17.8

405

15.9

Period of diagnosis

 1989-1992

447

2.1

93

1.9

112

2.1

115

2.3

80

2.0

47

1.8

<0.001

 

 1993-1995

1,070

4.9

284

5.8

230

4.3

248

5.0

201

5.0

107

4.2

 1996-1998

1,595

7.3

370

7.6

393

7.4

339

6.8

287

7.1

206

8.1

 1999-2001

2,585

11.9

639

13.0

616

11.5

569

11.4

475

11.7

286

11.3

 2002-2004

3,605

16.5

904

18.5

798

15.0

792

15.9

688

17.0

423

16.6

 2005-2007

5,870

26.9

1,371

28.0

1,259

23.6

1,439

28.9

1,097

27.1

704

27.7

 2008-2010

6,630

30.4

1,237

25.3

1,927

36.1

1,477

29.7

1,220

30.1

769

30.3

Stage at diagnosis

 Stage I

4,912

22.5

1,116

22.8

1,286

24.1

1,137

22.8

878

21.7

495

19.5

<0.001

<0.01

 Stage II

6,525

29.9

1,460

29.8

1,577

29.6

1,545

31.0

1,175

29.0

768

30.2

 Stage III

1,046

4.8

203

4.1

264

4.9

245

4.9

212

5.2

122

4.8

 Stage IV

516

2.4

99

2.0

127

2.4

120

2.4

98

2.4

72

2.8

 Missing

8,803

40.4

2,020

41.2

2,081

39.0

1,932

38.8

1,685

41.6

1,085

42.7

Smoking status

 Non-smoker

9,464

43.4

2,362

48.2

2,442

45.8

2,165

43.5

1,625

40.1

870

34.2

0.077

<0.001

 Current smoker

4,491

20.6

875

17.9

950

17.8

999

20.1

942

23.3

725

28.5

 Ex-smoker

6,705

30.8

1,449

29.6

1,711

32.1

1,539

30.9

1,227

30.3

779

30.6

 Current or Ex-smoker

384

1.8

52

1.1

64

1.2

92

1.8

101

2.5

75

3.0

 Missing

758

3.5

160

3.3

168

3.1

184

3.7

153

3.8

93

3.7

Alcohol drinking status

 Non-drinker

3,178

14.6

555

11.3

649

12.2

721

14.5

693

17.1

560

22.0

<0.001

<0.001

 Current drinker

12,294

56.4

2,841

58.0

3,184

59.7

2,803

56.3

2,195

54.2

1,271

50.0

 Ex-drinker

1,420

6.5

234

4.8

302

5.7

304

6.1

332

8.2

248

9.8

 Missing

4,910

22.5

1,268

25.9

1,200

22.5

1,151

23.1

828

20.5

463

18.2

  

A All cases1

21,802

100.0

4,898

22.5

5,335

24.5

4,979

22.8

4,048

18.6

2,542

11.7

  

Body mass index (kg/m2)

 <20

1,188

5.4

275

5.6

301

5.6

249

5.0

214

5.3

149

5.9

0.290

<0.001

 20-24

7,195

33.0

1,903

38.9

1,828

34.3

1,565

31.4

1,210

29.9

689

27.1

 25-29

6,455

29.6

1,390

28.4

1,611

30.2

1,528

30.7

1,171

28.9

755

29.7

 30+

4,542

20.8

812

16.6

978

18.3

1,081

21.7

986

24.4

685

26.9

 Missing

2,422

11.1

518

10.6

617

11.6

556

11.2

467

11.5

264

10.4

Charlson Comorbidity Score (CPRD data only)

 None recorded

16,662

76.4

4,024

82.2

4,133

77.5

3,758

75.5

2,949

72.9

1,798

70.7

<0.001

 

 1

3,597

16.5

640

13.1

842

15.8

869

17.5

741

18.3

505

19.9

 2

1,033

4.7

162

3.3

251

4.7

227

4.6

229

5.7

164

6.5

 3+

510

2.3

72

1.5

109

2.0

125

2.5

129

3.2

75

3.0

Consultations prior to diagnosis

 None recorded

1,070

4.9

199

4.1

247

4.6

262

5.3

231

5.7

131

5.2

<0.001

 

 1 to 5

8,076

37.0

1,939

39.6

2,007

37.6

1,862

37.4

1,428

35.3

840

33.0

 6 to 10

6,131

28.1

1,377

28.1

1,518

28.5

1,402

28.2

1,117

27.6

717

28.2

 11+

6,525

29.9

1,383

28.2

1,563

29.3

1,453

29.2

1,272

31.4

854

33.6

 Mean (sd)

8.8

(8.3)

8.5

(7.8)

8.6

(8.0)

8.6

(8.1)

9.2

(8.8)

9.6

(9.1)

Breast-related consultations prior to diagnosis

 None recorded

11,214

51.4

2,383

48.7

2,721

51.0

2,628

52.8

2,186

54.0

1,296

51.0

<0.001

 

 1

8,939

41.0

2,100

42.9

2,186

41.0

2,008

40.3

1,577

39.0

1,068

42.0

 2+

1,649

7.6

415

8.5

428

8.0

343

6.9

285

7.0

178

7.0

 Mean (sd)

0.58

(0.72)

0.62

(0.71)

0.60

(0.76)

0.56

(0.69)

0.55

(0.72)

0.58

(0.68)

Number of breast symptoms reported prior to diagnosis

 None recorded

10,406

47.7

2,298

46.9

2,542

47.6

2,428

48.8

1,967

48.6

1,171

46.1

<0.01

 

 1

9,664

44.3

2,182

44.5

2,356

44.2

2,218

44.5

1,759

43.5

1,149

45.2

 2

1,343

6.2

328

6.7

332

6.2

273

5.5

244

6.0

166

6.5

 3+

389

1.8

90

1.8

105

2.0

60

1.2

78

1.9

56

2.2

Number of days since last symptom report to diagnosis4

 Mean (range)

32.2

(1-547)

32.7

(1-541)

32.7

(1-547)

32.4

(1-545)

30.7

(1-541)

32.2

(1-541)

<0.05

 

Referrals prior to diagnosis

              

 None recorded

14,257

65.4

3,073

62.7

3,539

66.3

3,282

65.9

2,703

66.8

1,660

65.3

<0.001

 

 1

7,044

32.3

1,691

34.5

1,667

31.2

1,590

31.9

1,261

31.2

835

32.8

 2+

501

2.3

134

2.7

129

2.4

107

2.1

84

2.1

47

1.8

  

B Cases diagnosed 2005-20101

12,500

100.0

2,608

20.9

3,186

25.5

2,916

23.3

2,317

18.5

1,473

11.8

  

Charlson comorbidity score (HES data only)

 None recorded

11,774

94.2

2,512

96.3

3,032

95.2

2,742

94.0

2,137

92.2

1,351

91.7

<0.001

 

 1

451

3.6

64

2.5

101

3.2

107

3.7

110

4.7

69

4.7

 2

174

1.4

18

0.7

31

1.0

50

1.7

41

1.8

34

2.3

 3+

101

0.8

14

0.5

22

0.7

17

0.6

29

1.3

19

1.3

Charlson comorbidity score (CPRD or HES data)

 None recorded

8,931

71.4

2,059

78.9

2,332

73.2

2,042

70.0

1,548

66.8

950

64.5

<0.001

 

 1

2,185

17.5

353

13.5

534

16.8

541

18.6

455

19.6

302

20.5

 2

865

6.9

124

4.8

206

6.5

211

7.2

183

7.9

141

9.6

 3+

519

4.2

72

2.8

114

3.6

122

4.2

131

5.7

80

5.4

Time from diagnosis to first major surgery

 On or before diagnosis

919

7.4

176

6.7

202

6.3

206

7.1

169

7.3

166

11.3

0.064

0.106

 <=1 month

4,583

36.7

936

35.9

1,139

35.8

1,079

37.0

888

38.3

541

36.7

 <=2 months

2,733

21.9

574

22.0

727

22.8

645

22.1

504

21.8

283

19.2

 >2 months

588

4.7

114

4.4

153

4.8

141

4.8

115

5.0

65

4.4

 None recorded

3,677

29.4

808

31.0

965

30.3

845

29.0

641

27.7

418

28.4

Number of days from diagnosis to first major surgery5

 Mean (sd)

34.3

(28.4)

34.1

(27.8)

35.0

(28.9)

34.7

(29.8)

33.7

(27.4)

33.6

(27.3)

0.051

 
  1. 1Row percentages
  2. 2P-value for association between index variable and deprivation (multinomial regression for categorical variables and non-parametric tests for trend for continuous variables, see text)
  3. 3P-value for association between index variable and deprivation, excluding missing category (multinomial regression for categorical variables and non-parametric tests for trend for continuous variables, see text)
  4. 4Amongst the 6,302 patients who reported a breast symptom prior to diagnosis
  5. 5Amongst the 7,904 patients who had surgery after diagnosis
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