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Table 4 Overall Patient-Reported Outcomes by Study Group (Mixed Effects Model)

From: “Randomized trial of physical activity on quality of life and lung cancer biomarkers in patients with advanced stage lung cancer: a pilot study”

Score Type Score at Week 1 Intervention Group Usual Care Difference of score change P-value
Score at Week 12 Score Change Score at Week 12 Score Change
European Organisation for the Research and Treatment of Cancer (EORTC) Core Quality of life Questionnaire
Overall and Functioning Domains
  QLQ summary score 85.08 (2.16) 87.36 (2.64) 2.28 (2.18) 86.05 (2.79) 0.97 (2.22) 1.31 (3.02) 0.668
  Global health status (SE) 73.32 (3.67) 76.48 (4.35) 3.16 (4.11) 68.69 (4.77) −4.63 (4.20) 7.79 (5.51) 0.166
  Physical functioning 84.02 (2.79) 88.13 (3.10) 4.11 (2.50) 88.76 (3.31) 4.74 (2.54) −0.64 (3.41) 0.853
  Role functioning 85.51 (3.84) 93.60 (5.27) 8.09 (5.33) 76.55 (5.76) −8.95 (5.45) 17.04 (7.16) 0.022
  Emotional functioning 85.11 (2.74) 87.79 (3.07) 2.68 (2.89) 88.22 (3.38) 3.11 (2.95) −0.43 (3.83) 0.911
  Cognitive functioning 90.93 (2.74) 91.35 (3.02) 0.41 (2.26) 93.40 (3.22) 2.47 (2.31) −2.05 (3.13) 0.515
  Social functioning 83.91 (3.41) 79.69 (5.51) −4.22 (5.38) 88.31 (5.90) 4.40 (5.50) −8.62 (7.45) 0.254
Symptom Domains
  Fatigue 22.46 (3.51) 18.04 (5.54) −4.43 (4.85) 23.21 (5.79) 0.75 (4.97) −5.18 (6.88) 0.456
  Nausea and vomiting 6.32 (2.19) 3.88 (4.15) −2.44 (4.18) 12.53 (4.42) 6.21 (4.28) −8.65 (5.80) 0.144
  Pain 12.21 (4.06) 13.88 (4.79) 1.67 (4.77) 13.47 (5.29) 1.26 (4.87) 0.41 (6.28) 0.948
  Dyspnea 23.31 (4.06) 17.12 (5.15) −6.19 (4.88) 30.43 (5.60) 7.12 (4.99) −13.31 (6.62) 0.051
  Insomnia 19.64 (4.40) 20.22 (6.47) 0.58 (6.37) 16.15 (6.99) −3.49 (6.52) 4.07 (8.71) 0.643
  Appetite loss 12.24 (3.92) 8.08 (5.89) −4.16 (6.60) 17.19 (6.49) 4.95 (6.73) −9.11 (8.50) 0.290
  Constipation 14.84 (4.83) 13.63 (5.17) −1.21 (4.02) 3.64 (5.57) −11.19 (4.11) 9.99 (5.49) 0.077
  Diarrhoea 8.89 (3.64) 9.03 (3.77) 0.14 (3.32) 3.76 (4.15) −5.13 (3.39) 5.27 (4.38) 0.237
  Financial Difficulties 15.08 (4.76) 21.64 (6.72) 6.56 (4.54) 20.49 (6.76) 5.41 (4.65) 1.15 (6.49) 0.861
  MMRC Dyspnea Scale 1.03 (0.17) 0.99 (0.19) −0.04 (0.15) 0.96 (0.20) −0.07 (0.15) 0.03 (0.20) 0.889
  PHQ-9 Total Score (omits Q10) 3.55 (0.62) 2.72 (0.70) −0.83 (0.65) 3.86 (0.78) 0.31 (0.68) −1.14 (0.88) 0.203
  1. Notes
  2. EORTC Quality of life (QoL) score and functioning domains: higher score = better QoL/functioning.
  3. EORTC Symptom Domains: higher score = worse symptoms.
  4. MMRC Dyspnea Scale: higher score = worse dyspnea.
  5. PHQ-9: higher score = worse depressive symptoms.