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Table 7 Cox regression model testing the tumor microenvironment metascore as a continuous variable in the IMvigor 210 study

From: RB1 and TP53 co-mutations correlate strongly with genomic biomarkers of response to immunity checkpoint inhibitors in urothelial bladder cancer

 

Hazard Ratio

95% CI

P-value

ECOG (0 vs 1 or 2)

2.42

1.73–3.38

< 0.001 ***

TMB

0.96

0.94–0.98

< 0.001 ***

IC PD-L1

  

0.522

IC0 vs IC1

1.04

0.72–1.51

0.843

IC0 vs IC2+

0.84

0.55–1.28

0.416

Metascore

4.11

1.97–8.59

< 0.001 ***

  1. *** Statistically significant at p-value < 0.001