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Table 6 Multivariate Cox regression in the TCGA dataset intersecting with data from Knijnenburg et al. [21] (n = 399)

From: RB1 and TP53 co-mutations correlate strongly with genomic biomarkers of response to immunity checkpoint inhibitors in urothelial bladder cancer

 

Hazard Ratio

95% CI

P value

Age (< 60 vs > 60) **

1.85

1.24–2.77

0.003

Stage (II vs III and IV) **

1.90

1.28–2.83

0.001

T cells **

0.78

0.66–0.91

0.002

TMB **

0.94

0.91–0.97

< 0.001

Fibroblasts

1.18

0.98–1.42

0.076

  1. P value < 0.05 * < 0.01 **.