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Table 5 Initial Multivariate Cox regression in the TCGA dataset intersecting with data from Knijnenburg et al. [21] (n = 399)

From: RB1 and TP53 co-mutations correlate strongly with genomic biomarkers of response to immunity checkpoint inhibitors in urothelial bladder cancer

  Hazard Ratio 95% CI P value
Age (< 60 vs > 60) ** 1.81 1.21–2.70 0.004
Stage (II vs III and IV) ** 2.14 1.47–2.12 < 0.001
TMB** 0.93 0.89–0.98 0.007
No. DDR genes mutated 1.02 0.91–1.13 0.77
Sex 1.07 0.76–1.49 0.71
  1. P value < 0.05 * < 0.01 **.