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Table 5 Initial Multivariate Cox regression in the TCGA dataset intersecting with data from Knijnenburg et al. [21] (n = 399)

From: RB1 and TP53 co-mutations correlate strongly with genomic biomarkers of response to immunity checkpoint inhibitors in urothelial bladder cancer

 

Hazard Ratio

95% CI

P value

Age (< 60 vs > 60) **

1.81

1.21–2.70

0.004

Stage (II vs III and IV) **

2.14

1.47–2.12

< 0.001

TMB**

0.93

0.89–0.98

0.007

No. DDR genes mutated

1.02

0.91–1.13

0.77

Sex

1.07

0.76–1.49

0.71

  1. P value < 0.05 * < 0.01 **.
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BMC Cancer

ISSN: 1471-2407

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