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Table 4 Spearman bivariate correlation coefficients of DDR gene mutations, DDR deep deletions, predicted SNV neoantigens, Non-silent muts/Mb (TMB) and TILs fraction

From: RB1 and TP53 co-mutations correlate strongly with genomic biomarkers of response to immunity checkpoint inhibitors in urothelial bladder cancer

  No. DDR mutations No. DDR Deep deletions Predicted SNV neoantigens TMB TILs fraction
No. DDR mutations 1.00 0.09 0.77** 0.80** 0.26**
No. DDR Deep deletions 0.09 1.00 0.17** 0.19** −0.04
Predicted SNV neoantigens 0.77** 0.17** 1.00 0.95** 0.26**
TMB 0.80** 0.19** 0.95** 1.00 0.29**
TILs fraction 0.26** −0.04 0.26** 0.29** 1.00
  1. **P value < 0.01