Table 4 Risk factors for lymph node metastasis in validation cohort
From: A nomogram to predict lymph node metastasis risk for early esophageal squamous cell carcinoma
Variables | LNM | P value | Logistic regression analysis | P value | |
|---|---|---|---|---|---|
Negative (%) Positive (%) | OR 95%CI | ||||
Sex | 1.000 | – | – | ||
Male | 58 (84.1) | 11 (15.9) | |||
Female | 9 (81.8) | 2 (18.2) | |||
Age | 0.083 | – | – | ||
< 60 years | 24 (75.0) | 8 (25.0) | |||
> = 60 years | 43 (89.6) | 5 (10.4) | |||
Tumor location | 0.131 | – | – | ||
Upper | 6 (85.7) | 1 (14.3) | |||
Middle | 38 (77.6) | 11 (22.2) | |||
Lower | 23 (95.8) | 1 (4.2) | |||
Tumor number | 0.450 | – | – | ||
Single | 60 (84.5) | 11 (15.5) | |||
Mutifocal | 7 (77.8) | 2 (22.2) | |||
Tumor size | 0.014 | 2.674 1.876–6.320 | 0.008 | ||
< 2.5 cm | 46 (85.2) | 4 (14.8) | |||
> = 2.5 cm | 21 (80.8) | 9 (19.2) | |||
Differentiation | 0.008 | 3.902 1.843–10.354 | 0.005 | ||
High-middle | 58 (89.2) | 7 (11.8) | |||
Low | 9 (60.0) | 6 (40.0) | |||
Depth of invasion | 0.012 | 3.234 1.230–8.543 | 0.010 | ||
T1a | 30 (96.8) | 1 (3.2) | |||
T1b | 37 (75.5) | 12 (24.5) | |||