Table 3 Univariate and multivariate analysis of various prognostic factors

Covariates / different groups

%

p-value

%

p-value

%

p-value

Female

71.4

0.57

21.4

0.82

91

0.74

Male

72.2

40

87

Age < 21

69.2

0.56

48.4

0.151

95.5

0.71

Age > 21

75.1

26

81.6

Age < 30

69

0.55

45.8

0.29

97

0.093

Age > 30

79.3

18.6

71

Performance status 0–1

71.7

*

33.7

0.54

87

0.48

Performance status > 2

100

0

75

B symptoms - No

71.6

*

34.4

0.98

88.4

0.86

B symptoms - Yes

100

57.1

87.5

Hemoglobin > 10.5

77.7

0.9

50.5

0.011

86.8

0.13

Hemoglobin < 10.5

85.7

16.7

67

Albumin > 4

80.2

0.047

53.8

0.005

92

0.061

Albumin < 4

60

20

70

LDH not elevated

82.7

0.007

67.3

0.012

100

0.025

LDH elevated

61

19

75

Bulky disease No

73

0.59

35.5

0.26

89.2

0.72

Bulky disease Yes

85.7

31.8

81

Spleen involvement - No

72.2

*

38.6

0.058

89.2

0.8

Spleen involvement - Yes

100

27.1

84.4

Extranodal involvement - No

72.4

0.72

34.7

0.34

87

0.51

Extranodal involvement - Yes

66.7

32.8

87.5

Bone marrow positive

–

–

34.2

0.35

86.4

0.46

Bone marrow negative

0

100

GHSG - Early favorable

79

–

–

GHSG - Early Unfavorable

60.2

0.04

Radiation given

79.2

0.03

50

0.27

75

0.91

Radiation not given

63.8

35

86

HR**

95% CI**

HR

95% CI (range)

HR

95% CI (range)

GHSG Early favorable

1

–

–

–

-***

GHSG Early unfavorable

3.84

1.44 -10.25

Hemoglobin > 10.5

–

–

1

–

–

Hemoglobin < 10.5

4.862

1.5-15.76

Albumin > 4

–

–

1

–

–

Albumin < 4

4.359

1.492-12.74