Table 3 Selected papers on PM for bone sarcoma with prognostic factors for OS and PFS
First author | Year | Histology | Number of patients with PM | 5-year OS | Prognostic factors for OS | Prognostic factors for PFS |
|---|---|---|---|---|---|---|
Ahmed, 2019 [4] | 2008–2016 | OST | 88 | 38% | lung metastasis diagnosed during initial CHT(W) > 3 metastases (W) | lung metastasis diagnosed during initial CHT(W) > 3 metastases (W) |
Briccoli, 2010 [10] | 1985–2005 | OST | 323 | 37% | - | Metastasis at time of diagnosis (W) Number of PM (1 (B) vs. ≥2 (W)) DFI (24 months (B) vs. 12–24 vs. < 12(W)) |
Chen, 2008 [5] | 1989–2007 | OST | 23 | 31% | m < 5 metastases (B) m Pulmonary metastases not identified during pre- and post-operative chemotherapy (B) | < 5 metastases (B) |
Harting, 2006 [6] | 1980–2000 | OST | 93 | 29% | PM (B) compared to no PM (W) m DFI ≥1y (B) | – |
Letourneau, 2011 [9] | 1990–2006 | ES | 10 | 80% | PM (B) compared to no PM (W) | PM (B) compared to no PM (W) |
Briccoli, 2004 [11] | 1972–1997 | ES | 24 | 56% | PM (B) compared to no PM (W) | – |
Sambri, 2019 [7] | 1992–2017 | CS | 29 | 55% | m PM (B) compared to no PM (W) m Bilateral metastases (W) m > 1 metastases (W) | – |