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Table 4 Overall survival analysis in advanced-stage patients who received or did not receive angiogenesis inhibitors

From: Assessing tumor angiogenesis using dynamic contrast-enhanced integrated magnetic resonance-positron emission tomography in patients with non-small-cell lung cancer

  2-year overall survival (%) p-value*
Angiogenesis inhibitors received
(n = 11)
Angiogenesis inhibitors not received
(n = 47)
MTV (cm3)
  ≥ 30 100.0 48.1 0.046
  < 30 71.4 71.4 0.334
Ktrans (10−3 min−1)
  ≥ 200 85.7 60.3 0.069
  < 200 66.7 57.8 0.436
kep (10−3 min−1)
  ≥ 900 85.7 59.3 0.048
  < 900 66.7 57.8 0.488
  1. Abbreviations: MR-PET = magnetic resonance positron emission tomography; MTV = metabolic tumor volume; Ktrans = volume transfer constant; kep = reverse reflux rate constant
  2. * Significance was tested using Kaplan–Meier analysis and log-rank tests
  3. p-values < 0.05 were considered statistically significant
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