Fig. 3
Relationships between MR-PET parameters and serum angiogenesis-related biomarkers in patients with non-small-cell lung carcinoma. Scatterplots demonstrating the relationships between serum VEGF-A (pg/mL), angiogenin (ng/mL), and angiopoietin-1 (10− 1 ng/ml) concentrations and (a) metabolic tumor volume (MTV), (b) SUVmax, (c) ADC, (d) Ktrans, (e) kep, (f) ve, (g) vp, and (h) iAUC60. P-values for statistical comparisons between MR-PET parameters and serum angiogenesis-related biomarkers were obtained using Pearson’s linear regression analysis. When Bonferroni correction was applied for multiple comparisons (a total of eight MR-PET derived parameters), p-values < 0.006 were considered statistically significant