Fig. 4

WGCNA and enrichment analysis. a Scale-free fit index analysis for various soft-thresholding powers, cut-off > 0.85. The mean connectivity analysis for various soft-thresholding powers. b The cluster dendrogram of DEGs. In the figure, each branch represents one gene, and each colour indicates a co-expression module. The grey refers to genes that cannot be classified in any module. c Heatmap of the correlation between module eigengenes and the clinical traits of HCC. The green module was most relevant to the OS events and OS time. d The top 50 hub genes in the green module. The genes are represented as nodes; node size is related to connectivity of the gene by degree, and edge size is related to weight. e Enrichment analysis of immune hub genes. Left: The x axis represents the functional terms that are grouped and colour-coded according to data sources. The y-axis indicates the adjusted p-values on a negative-log10 scale. Every circle is one term and is sized according to the term enrichment degree. Right: the table of interesting enrichment results