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Table 1 Characteristics of patients in the study population

From: The role of EORTC QLQ-C15-PAL scores and inflammatory biomarkers in predicting survival in terminally ill patients with cancer

 

Number (%)

Total Number of Patients

130

Age, years (median, range)

74 (32–97)

Sex (Male/Female)

71 (54.6)/59 (45.4)

Primary Cancer Site

 Lung

31 (23.8)

 Colon

26 (20.0)

 Pancreas

12 (9.2)

 Liver

7 (5.4)

 Stomach

7 (5.4)

 Esophagus

5 (3.8)

 Breast

5 (3.8)

 Ovary

4 (3.1)

 Uterine

4 (3.1)

 Prostate

3 (2.3)

 Other

23 (17.7)

 Unknown

3 (2.3)

Metastasis (total number)

 Liver

54 (41.5)

 Lung

52 (40.0)

 Bone

40 (30.8)

 Brain

14 (10.8)

PPS

  ≥ 70

20 (15.4)

 40–60

74 (56.9)

  ≤ 30

29 (22.3)

 Unknown

7 (5.4)

Survival, days (median, range) n = 109

18 (2–193)

QLQ-C15-PAL (median (Q1, Q3), mean (± SD))

 Physical Functioning (n = 125)

33.3 (20.0, 46.7), 37.0 ± 25.1

 Emotional Functioning (n = 129)

66.7 (41.7, 83.3), 63.2 ± 28.3

 Dyspnea

33.3 (0.0, 66.7), 39.5 ± 34.4

 Pain (n = 129)

50.0 (16.7, 66.7), 47.3 ± 34.0

 Insomnia

33.3 (0.0, 66.7), 40.0 ± 36.0

 Appetite Loss

66.7 (33.3, 100), 57.7 ± 38.4

 Constipation (n = 128)

33.3 (0.0, 66.7), 37.0 ± 35.3

 Fatigue (n = 129)

66.7 (44.4, 100), 63.8 ± 29.7

 Nausea/Vomiting

0.0 (0.0, 16.7), 18.7 ± 29.6

 QOL (n = 124)

50.0 (16.7, 50.0), 38.7 ± 27.1

Inflammatory Biomarkers (median, range) n = 126

 CRP (mg/dL)

3.9 (<  0.1–32.1)

 Alb (g/dL)

2.6 (1.2–3.9)

 NLR (n = 122)

7.6 (0.6–187)

  1. Alb albumin, CRP C-reactive protein, NLR neutrophil-lymphocyte ratio, PPS Palliative Performance Scale, QLQ-C15-PAL European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 15 Palliative Care, QOL quality of life
  2. In the QLQ-C15-PAL, patients rated their symptoms using a 4-point scale (1 = not at all, 2 = a little, 3 = quite a bit, 4 = very much) for two functional domains and 7 symptom domains, and a 7-point scale (range: 1 = very poor to 7 = excellent) for overall QOL. All scale scores were linearly transformed, and the resultant scores ranged from 0 to 100. Q1: first quarter (25% quartile), Q3: third quarter (75% quartile), SD: standard deviation