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Table 3 Odds ratios of patients bothered by skin symptoms for factors in baseline characteristics and skin conditions

From: Radiation-irritated skin and hyperpigmentation may impact the quality of life of breast cancer patients after whole breast radiotherapy

Depression due to the skin problems

 

Crude

Adjusted*#

Factor

OR (95% CI)

OR (95% CI)

Age, years

  < 30

4.29 (0.65, 28.26)

7.84 (0.98, 62.69)

 30–40

1.43 (0.30, 6.89)

2.00 (0.35, 11.53)

 40–50

1.85 (0.40, 8.55)

2.35 (0.43, 12.74)

 50–60

1.05 (0.21, 5.34)

1.13 (0.19, 6.77)

  > = 60

1 (Reference)

1 (Reference)

Sweating in the radiation field

 Normal sweating

1 (Reference)

1 (Reference)

 Absent sweating

1.86 (0.81, 4.24)

1.36 (0.55, 3.33)

 Absent sweating and hotness

5.92 (2.65, 13.20)

4.13* (1.67, 10.20)

Dryness in the radiation field

 Normal moisture

1 (Reference)

1 (Reference)

 Dry skin

3.62 (1.45, 9.01)

2.42 (0.89, 6.61)

 Dry skin and itchy

4.41 (1.80, 10.79)

1.44 (0.49, 4.27)

Skin color deposition

 No skin color deposition

1 (Reference)

1 (Reference)

 Mild skin color deposition

5.38 (1.87, 15.43)

4.26* (1.41, 12.83)

 Severe skin color deposition

10.40 (3.54, 30.54)

8.30* (2.61, 26.42)

Interval after radiotherapy, months

  < 1

0.69 (0.27, 1.81)

0.33* (0.11, 0.96)

 1–6

0.88 (0.43, 1.77)

0.58 (0.26, 1.29)

 6–12

0.97 (0.47, 2.00)

0.56 (0.24, 1.29)

 12–24

1.28 (0.63, 2.56)

1.32 (0.59, 2.96)

  > 24

1 (Reference)

1 (Reference)

  1. *: When a 95% CI does not include the value of 1, it is indicated that there is a tendency among factor levels
  2. #: Multivariable analysis including age, operation, chemotherapy, interval after radiotherapy, sweating, dryness, seasonal skin irritation, post-RT skin disorder and skin color deposit