Skip to main content
Fig. 1 | BMC Cancer

Fig. 1

From: KLF5-mediated Eppk1 expression promotes cell proliferation in cervical cancer via the p38 signaling pathway

Fig. 1

Eppk1 expression increases in cervical cancer tissues and cell lines. a Heatmap shows a subset of the differentially expressed mRNAs detected in 3 cervical cancer tissues and 3 normal tissues (control) by micro array analysis. b QRT-PCR verifies seven changed genes. ***P < 0.001 vs. control. c, d mRNA expression of Eppk1 (c) and correlation analysis between mRNA expression of Eppk1 and KLF5 (d) in cervical squamous cell carcinoma (CSCC) from the Cancer Genome Atlas (TCGA) database. e Expression level of Eppk1 and KLF5 protein in C33A, HeLa and SiHa cells. f Immunofluorescence staining of KLF5 (red) and Eppk1 (green) in CC tissues (n = 40), cervical intraepithelial neoplasia (CIN) tissues (CIN I: 31 cases; CIN II-III: 47 cases) and control (n = 37). Scale bars = 100 μm. Right: Statistical analysis of fluorescence intensity. *P < 0.05 and **P < 0.01 vs. control

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us