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Table 5 KEGG pathway of validated target genes of miR-221-3p

From: Bioinformatics analysis of the expression and role of microRNA-221-3p in head and neck squamous cell carcinoma

KEGG ID

KEGG term

Count (%)

Gene symbol

p-value

hsa00982

Drug metabolism - cytochrome P450

7

GSTA1, UGT1A7, CYP3A5, FMO2, MAOB, ADH1C, ADH1B

3.18E-07

hsa00980

Metabolism of xenobiotics by cytochrome P450

6

GSTA1, UGT1A7, CYP3A5, CYP2F1, ADH1C, ADH1B

8.10E-06

hsa00830

Retinol metabolism

5

UGT1A, ALDH1A1, CYP3A5, ADH1C, ADH1B

6.43E-05

hsa05204

Chemical carcinogenesis

5

GSTA1, UGT1A7, CYP3A5, ADH1C, ADH1B

1.69E-04

hsa00350

Tyrosine metabolism

3

MAOB, ADH1C, ADH1B

1.54E-03

  1. Notes: KEGG: Kyoto Encyclopedia of Genes and Genomes