Skip to main content

Table 2 The correlation between miR-221-3p expression levels and clinic characteristics based on TCGA database

From: Bioinformatics analysis of the expression and role of microRNA-221-3p in head and neck squamous cell carcinoma

Clinicopathological features Terms n Mean ± SD p-value
Unpaired tissue Normal 44 8.16 ± 0.64 0.001
HNSCC 480 8.55 ± 0.78  
Sex Male 383 8.45 ± 0.79 0.001
Female 141 8.71 ± 0.68  
Age < 60 234 8.50 ± 0.76 0.559
> = 60 290 8.54 ± 0.78  
lymphovascular invasion NO 232 8.54 ± 0.81 0.429
YES 292 8.49 ± 0.75  
Neoplasm histologic grade G1-G2 371 8.49 ± 0.73 0.260
G3-G4 156 8.58 ± 0.82  
M stage M0 498 8.51 ± 0.78 0.967
M1 29 8.51 ± 0.57  
N stage N0 246 8.53 ± 0.76 0.572
N1-N3 281 8.49 ± 0.77  
Alcohol NO 164 8.62 ± 0.76 0.047
YES 363 8.48 ± 0.76  
HPV status Negative 194 8.41 ± 0.81 0.066
Positive 330 8.55 ± 0.81  
Perineural invasion NO 198 8.53 ± 0.81 0.693
YES 329 8.50 ± 0.80
  1. Notes: HNSCC, Head and neck squamous cell carcinoma; T stage, size or direct extent of the primary tumor; N stage, degree of spread to regional lymph nodes; M stage, presence of distant metastasis; SD, standard deviation