Fig. 4

The development of GSM PDX model. a Flow diagram of tumor cell isolation to generate GSM primary cell line using ex vivo explant culture, and to establish animal PDX tumor model. b Cell morphology of explant culture under light microscope at 40X and 100X magnification. Arrowhead indicates the tumor explant tissue. c PDX tumor growth of sequential in vivo tumor passage P2 to P4 in NOD-SCID mice