Fig. 6From: Detection of tumor-derived extracellular vesicles in plasma from patients with solid cancerMutation analysis of human breast cancer cell lines by digital PCR. The figure shows dPCR dot plots for cellular mRNA (a, c, e and g) and matched EV-RNA (b, d, f and h) indicating wild-type (WT) and mutant (MT) copies for breast cancer cell lines BT20 (PIK3CA p.H1047R), T47D (PIK3CA p.H1047R), MDA-MB-435 (BRAF p.V600E(c.1799T > A)) and MDA-MB-231 (KRAS p.G13D). Dots represent wells with mutant copies (blue), wild-type copies (red), both wild-type and mutant copies (green), empty wells (yellow), and undetermined wells (grey). VAF: Variant Allele FrequencyBack to article page