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Table 1 Subjects’ Characteristics of Training Study

From: A prediction model based on DNA methylation biomarkers and radiological characteristics for identifying malignant from benign pulmonary nodules

Characteristics

Subjects with Malignant PNs

(n = 63)

Subjects with Benign PNs

(n = 47)

Clinical

Age (Years)

  Median Age

58

55

  Age Range

36–77

26–70

Sex

  Male

36

27

  Female

27

20

Smoking history

  Non-smoker

30

39

  Ex-smoker

12

3

  Current smoker

21

5

Smoking pack-years

  Mean Pack-years (Smokers only)

36.52

20

  Years quit (Smoker sonly)

8.9

3

Histology subtype

  Adenocarcinoma

37

 

  Squamous cell carcinoma

14

 

  Small cell lung cancer

8

 

  Other

4

 

Stage

  I

17

 

  II

21

 

  III-IV

25

 

Radiological

  Nodule size (mm)

21.46 (SD 10.52)

11.89 (SD 6.81)

Nodule location

  Left lower lobe

9

6

  Left upper lobe

17

12

  Right lower lobe

15

15

  Right middle lobe

3

4

  Right upper lobe

19

10

Nodule type (number)

  Nonsolid or ground-glass opacity

17

13

  Perifissural

6

5

  Part-solid

9

8

  Solid

13

11

  Spiculation

18

10

  1. PN pulmonary nodule, SD standard deviation