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Table 2 Candidate marker of phospholipids to discriminate CRLM

From: A new rapid diagnostic system with ambient mass spectrometry and machine learning for colorectal liver metastasis

m/z

Candidate molecule

Median ion intensity

P value (āˆ’log10)

Non-cancer

CRLM

Dominant in non-cancer liver specimen

ā€ƒ760.50

PE (38:7ā€“16:1/22:6)

12,970.0

0.0

28.3

ā€ƒ712.50

PE (34:3ā€“16:0/18:3)

19,792.0

0.0

27.7

ā€ƒ788.55

PE (40:7ā€“18:1/22:6)

153,466.0

0.0

26.8

ā€ƒ806.50

PS (40:7ā€“18:1/22:6)

8562.0

0.0

27.0

ā€ƒ863.55

PI (36:1ā€“16:0/20:1)

8974.0

0.0

25.6

ā€ƒ762.50

PE (38:6ā€“16:0/22:6)

2,058,266.0

57,728.0

25.5

ā€ƒ736.50

PE (36:5ā€“16:0/20:5)

121,756.0

11,973.0

25.4

ā€ƒ850.55

PC (38:6ā€“16:0/22:6)

480,734.0

29,393.0

25.4

ā€ƒ738.50

PE (36:4ā€“16:0/20:4)

566,367.0

63,337.0

25.4

ā€ƒ790.55

PE (40:6ā€“18:0/22:6)

1,171,554.0

66,685.0

25.4

Dominant in CRLM specimen

ā€ƒ747.55

SM (34:1-d18:1/16:0)

175,390.0

375,704.0

20.2

ā€ƒ830.60

PC (36:2ā€“16:0/20:2)

0.0

9619.0

19.9

ā€ƒ800.60

PE (40:1ā€“18:1/22:0)

0.0

17,383.0

18.6

ā€ƒ856.60

PC (38:3ā€“18:1/20:2)

0.0

8239.0

18.2

ā€ƒ768.55

PE (38:3ā€“18:1/20:2)

0.0

39,983.0

16.3

ā€ƒ858.60

PC (38:2ā€“18:1/20:1)

0.0

18,930.0

16.3

ā€ƒ766.55

PE (38:4ā€“18:2/20:2)

0.0

17,581.0

14.1

ā€ƒ830.60

PC (36:2ā€“16:1/20:1)

0.0

8761.0

10.9

ā€ƒ716.55

PE (34:1ā€“16:1/18:0)

0.0

65,533.0

10.9

ā€ƒ786.55

PS (36:2ā€“18:1/18:1)

0.0

3703.0

8.4

  1. CRLM colorectal liver metastasis, PE phosphatidylethanolamine, PC phosphatidylcholine, SM sphingomyelin, LPC lysophosphatidylcholine