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Fig. 3 | BMC Cancer

Fig. 3

From: Circ_0003266 sponges miR-503-5p to suppress colorectal cancer progression via regulating PDCD4 expression

Fig. 3

MiR-503-5p was a direct target of circ_0003266. a. Circular RNA Interactome was used to predict the binding site between circ_0003266 and miR-503-5p. b. Dual-luciferase reporter gene assay was used to confirm the relationship between circ_0003266 and miR-503-5p. c. qRT-PCR was used to detect the expression of miR-503-5p in SW480 and HCT-116 cells transfected with NC, circ_0003266 overexpression plasmids, si-NC, or si-circ_0003266. d. qRT-PCR was used to detect the expression of miR-503-5p in human CRC tissues and adjacent tissues. e. Pearson correlation analysis showed the negative relationship between circ_0003266 and miR-503-5p in CRC tissues. ***P < 0.001

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