Table 1 Top 30 hub genes in the PPI network
mRNA | Degree | Expression | mRNA | Degree | Expression | mRNA | Degree | Expression |
|---|---|---|---|---|---|---|---|---|
MYC | 65 | up | RRM2 | 32 | up | CCNE1 | 25 | up |
VEGFA | 54 | up | CDC25A | 30 | up | CEP55 | 25 | up |
CCND1 | 45 | up | CDKN1A | 30 | down | RACGAP1 | 24 | up |
EZH2 | 45 | up | PCNA | 30 | up | ESPL1 | 24 | up |
CCNB1 | 44 | up | KPNA2 | 29 | up | RAD51AP1 | 24 | up |
CCNA2 | 42 | up | E2F1 | 29 | up | E2F7 | 24 | up |
CHEK1 | 40 | up | DLGAP5 | 28 | up | CCNF | 23 | up |
MCM7 | 37 | up | KIF23 | 28 | up | CLSPN | 22 | up |
MKI67 | 34 | up | MYBL2 | 28 | up | KAT2B | 20 | down |
BIRC5 | 32 | up | TRIP13 | 28 | up | MET | 20 | up |