Characteristic | Unadjusted HR (95%CI) | Adjusteda HR (95%CI) | Adjusted p |
---|---|---|---|
Sex | |||
Female | 1 | 1 | |
Male | 1.56 (1.24–1.96) | 1.38 (1.08–1.76) | 0.011 |
Age | |||
≤ 49 | 1 | 1 | |
50–59 | 2.11 (1.14–3.89) | 2.2 (1.18–4.08) | 0.013 |
60–69 | 1.80 (1.00–3.25) | 1.87 (1.02–3.4) | 0.042 |
70–79 | 1.45 (0.80–2.64) | 1.58 (0.86–2.92) | 0.14 |
80 ≥ | 1.67 (0.84–3.31) | 1.93 (0.96–3.88) | 0.065 |
Comorbidities (yes vs no) | |||
Diabetes | 0.94 (0.71–1.26) | 1.06 (0.78–1.43 | .716 |
Cardiovascular | 0.84 (1.05–1.43) | 0.89 (0.69–1.14) | .347 |
Atrial fibrillation | 1.00 (0.78–1.30) | 0.99 (0.75–1.31) | .956 |
COPD | 0.99 (0.80–1.25) | 0.9 (0.71–1.13) | 0.353 |
Disease status | |||
Newly diagnosed | 1.14 (0.88–1.47) | 1.26 (0.96–1.65) | .009 |
Recurrence | 1 | 1 | |
Stage | |||
II | 0.87 (0.21–3.52) | 1.18 (0.28–4.98) | .824 |
III | 1 | 1 | |
IV | 0.96 (0.76–1.20) | 1.11 (0.87–1.4) | .402 |
Histology | |||
Adenocarcinoma | 1 | 1 | |
Squamous | 1.58 (1.21–2.06) | 1.54 (1.15–2.08) | .004 |
SCLC | 1.63 (1.19–2.24) | 1.48 (1.07–2.05) | .019 |
Other | 1.70 (1.29–2.24) | 1.59 (1.18–2.14) | .002 |
Other cancer treatment | |||
Radiotherapy | 1.02 (0.83–1.26) | 0.9 (0.72–1.12) | .334 |