Skip to main content

Table 10 For genes with at least five hemimethylation sites in normal samples

From: Statistical and bioinformatic analysis of hemimethylation patterns in non-small cell lung cancer

Gene name

Count

Family

Gene Description

ZFPM1

14

TF

zinc finger protein, FOG family member 1

GNAS

13

OG

GNAS complex locus

RGPD2

12

RANBP2 like and GRIP domain containing 2

SHANK3

11

SH3 and multiple ankyrin repeat domains 3

IRX2

10

TF, HP

iroquois homeobox 2

LTB4R

9

leukotriene B4 receptor

CPEB3

8

cytoplasmic polyadenylation element binding protein 3

PTPRN2

7

protein tyrosine phosphatase receptor type N2

MIR1268A

7

microRNA 1268a

GNAS-AS1

7

GNAS antisense RNA 1

CYP26C1

7

cytochrome P450 family 26 subfamily C member 1

TBL1XR1

6

transducin beta like 1 X-linked receptor 1

HOXA3

6

TF, HP

homeobox A3

CACNA1H

6

calcium voltage-gated channel subunit alpha1 H

NPEPPS

6

aminopeptidase puromycin sensitive

SEMA6B

6

CGF

semaphorin 6B

HOMER3

6

homer scaffold protein 3

PINLYP

6

phospholipase A2 inhibitor and LY6/PLAUR domain containing

GDI1

6

GDP dissociation inhibitor 1

HS3ST2

6

heparan sulfate-glucosamine 3-sulfotransferase 2

PRDM16

5

TF, OG, TCG

PR/SET domain 16

PLK3

5

PK

polo like kinase 3

GREM2

5

CGF

gremlin 2, DAN family BMP antagonist

MEIS1

5

TF, HP

Meis homeobox 1

MEIS1-AS2

5

MEIS1 antisense RNA 2

POLH

5

DNA polymerase eta

HOXA-AS2

5

HOXA cluster antisense RNA 2

EBF3

5

EBF transcription factor 3

CBFA2T3

5

TF, OG, TCG

CBFA2/RUNX1 translocation partner 3

RPL13

5

ribosomal protein L13

NFIC

5

TF

nuclear factor I C

CDH4

5

cadherin 4

PDGFB

5

OG, TCG

cytokine or growth factor, platelet derived growth factor subunit B

CCNT1

5

cyclin T1

SNORD68

5

small nucleolar RNA, C/D box 68

  1. The gene name, corresponding number of hemimethylated sites (i.e., count), specified gene family, and a description of the gene are formatted in the table’s respective columns. Descriptions are derived from the Molecular Signature Database [14] and the GeneCards database [15]. Certain genes are indicated as members of specific gene families, as shown in the third column: “TF” for transcription factor, “TS” for tumor suppressor, “OG” for oncogene, “HP” for homeodomain protein, “TCG” for translocated cancer gene, and “PK” for protein kinase