Fig. 1

The comparison of ATRX mutation frequency between female and male patients. a Comparison of somatic mutation profiles between female and male GC patients. ATRX is the only gene found to significantly occur more in female patients compared to male patients (FDR = 0.0108). b Proportion of ATRX mutation in female and male GC patients in cohort of GACA-CN and GACA-JP. c Comparison of ATRX mutation frequency between female and male patients with various tumor types from ICGC database. ***, P < 0.001; **, P < 0.01; *, P < 0.05