Table 2 Correlation between clinicopathological factors and CAF PD-L1 expression (73–10 assay)
Factors | PD-L1-positive (n = 34) | PD-L1-negative (n = 27) | p-value |
|---|---|---|---|
Age (years old; median ± SD) | |||
66 ± 13 | 65 ± 17 | 0.907 | |
Menopausal status | |||
premenopausal | 4 | 5 | 0.482 |
postmenopausal | 30 | 21 | |
unknown | 0 | 1 | |
Tumour size (mm) | |||
≤ 20 | 17 | 14 | 1.000 |
> 20 | 17 | 13 | |
Pathological stage | |||
I + II | 30 | 23 | 1.000 |
III | 4 | 4 | |
Lymph node status | |||
positive | 8 | 6 | 0.741 |
negative | 22 | 11 | |
not tested | 4 | 10 | |
Lymphatic invasion | |||
positive | 30 | 22 | 0.492 |
negative | 4 | 5 | |
Venous invasion | |||
positive | 19 | 18 | 0.439 |
negative | 15 | 9 | |
Nottingham histlogical grade | |||
1 + 2 | 17 | 12 | 0.797 |
3 | 17 | 15 | |
Ki-67 labeling index (LI) | |||
high | 18 | 10 | 0.424 |
low | 15 | 14 | |
not tested | 1 | 3 | |
Stromal TILs | |||
LPB | 13 | 6 | 0.266 |
non-LPBC | 21 | 21 | |
PD-L1 on stromal TILs (73–10) | |||
positive | 29 | 8 | < 0.001 |
negative | 5 | 19 | |
Adjuvant chemotherapy | |||
performed | 18 | 16 | 1.000 |
not performed | 13 | 11 | |
undetermined | 3 | 0 | |