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Table 6 Multivariate Cox Regression for OS among patients of Breast Cancer Liver Metastases with or without HER2-targeted therapy in the FUSCC dataset

From: Risk and prognostic factors of breast cancer with liver metastases

Variable

Overall Survival With HER2-targeted therapy

Overall Survival Without HER2-targeted therapy

HR (95% CI)

P Value

HR (95% CI)

P Value

Subtype

HR+/HER2−

1[Reference]

 

1[Reference]

 

HR+/HER2+

0.74 (0.58–0.95)

0.017*

2.62 (1.88–3.66)

< 0.001*

HR−/HER2+

0.81 (0.63–1.05)

0.110

3.43 (2.29–5.15)

< 0.001*

Triple-negative

2.17 (1.78–2.63)

< 0.001*

2.17 (1.78–2.63)

< 0.001*

  1. Adjust for other variables
  2. + denotes positive; − denotes negative; * denotes a statistically significant P-value; HER2 Human epidermal growth factor receptor 2, HR Hormone receptor, CI Confidence interval