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Table 6 Multivariate Cox Regression for OS among patients of Breast Cancer Liver Metastases with or without HER2-targeted therapy in the FUSCC dataset

From: Risk and prognostic factors of breast cancer with liver metastases

Variable Overall Survival With HER2-targeted therapy Overall Survival Without HER2-targeted therapy
HR (95% CI) P Value HR (95% CI) P Value
Subtype
HR+/HER2− 1[Reference]   1[Reference]  
HR+/HER2+ 0.74 (0.58–0.95) 0.017* 2.62 (1.88–3.66) < 0.001*
HR−/HER2+ 0.81 (0.63–1.05) 0.110 3.43 (2.29–5.15) < 0.001*
Triple-negative 2.17 (1.78–2.63) < 0.001* 2.17 (1.78–2.63) < 0.001*
  1. Adjust for other variables
  2. + denotes positive; − denotes negative; * denotes a statistically significant P-value; HER2 Human epidermal growth factor receptor 2, HR Hormone receptor, CI Confidence interval