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Table 2 Global metrics of the drug combination lovastatin plus cisplatin in three cell lines: A549 (lung adenocarcinoma), HT29 (colon adenocarcinoma) and MCF7 (breast carcinoma), in comparison to the metrics obtained in similar Saccharomyces cerevisiae analyses

From: Complex interactions of lovastatin with 10 chemotherapeutic drugs: a rigorous evaluation of synergism and antagonism

Metrics S. cerevisiae A549 HT29 MCF7
Day 2 Day 3 Day 2 Day 3 Day 2 Day 3 Day 2 Day 3
SUM_SYN_ANT −2.335 −3.553 −7.642 −9.875 −5.887 − 3.117 −33.789 −13.498
SYN_MAX 13.895 15.698 6.014 4.812 15.346 11.252 12.558 4.922
ANT_MAX −45.256 −35.016 −35.744 −43.200 −51.294 −55.074 −73.647 − 35.777