Table 2 Global metrics of the drug combination lovastatin plus cisplatin in three cell lines: A549 (lung adenocarcinoma), HT29 (colon adenocarcinoma) and MCF7 (breast carcinoma), in comparison to the metrics obtained in similar Saccharomyces cerevisiae analyses
Metrics | S. cerevisiae | A549 | HT29 | MCF7 | ||||
|---|---|---|---|---|---|---|---|---|
Day 2 | Day 3 | Day 2 | Day 3 | Day 2 | Day 3 | Day 2 | Day 3 | |
SUM_SYN_ANT | −2.335 | −3.553 | −7.642 | −9.875 | −5.887 | − 3.117 | −33.789 | −13.498 |
SYN_MAX | 13.895 | 15.698 | 6.014 | 4.812 | 15.346 | 11.252 | 12.558 | 4.922 |
ANT_MAX | −45.256 | −35.016 | −35.744 | −43.200 | −51.294 | −55.074 | −73.647 | − 35.777 |