Comparison of clinicopathological features and long-term prognosis between mixed predominantly differentiated-type and pure differentiated-type early gastric cancer

Table 1 Demographic and clinicopathological characteristics of the patients

All	n (%)
Age (years)
Mean (range)	71.8 (38–91)
Sex
Male	351 (76.5)
Female	108 (23.5)
Location
Upper third	103 (22.4)
Middle third	157 (34.2)
Lower third	199 (43.4)
Macroscopic type
Elevated (I,IIa)	146 (31.8)
Flat (IIb)	4 (0.9)
Depressed (IIc, III)	256 (55.8)
Complex (elevated + depressed)	53 (11.5)
Tumor size (mm)
Mean (range)	21.9 (1–128)
Depth
Mucosa	330 (71.9)
Submucosa, < 500 μm	59 (12.9)
Submucosa, ≥500 μm	70 (15.2)
Histological type
PD (pure differentiated)	409 (89.1)
MD (mixed predominant differentiated)	50 (10.9)
Lymphatic invasion	35 (7.6)
Vascular invasion	24 (5.2)
Ulceration	66 (14.4)
First treatment
ESD	396 (84.5)
Gastrectomy	63 (14.7)
Vertical margin + or x (for ESD)	15 (3.8)
Horizonal margin + or x (for ESD)	2 (0.5)
Non-curative resection (for ESD)	61 (15.4)
Additional gastrectomy (for non-curative ESD)	44 (72.1)
LNM	11 (2.4)

Abbreviations: PD pure differentiated-type, MD mixed differentiated-type, ESD endoscopic submucosal dissection, LNM lymph node metastasis

ISSN: 1471-2407